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題名 | Preparation of [fedf]Sm-EDTMP: Its Quality Control and Biodistribution=釤-153-EDTMP之製備:其品質管制與生物體分佈研究 |
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作者姓名(外文) | Mushtaq,A.; Jawaid,M.; Ishfaq,M. M.; | 書刊名 | 核子科學 |
卷期 | 34:3 1997.06[民86.06] |
頁次 | 頁196-202 |
分類號 | 449.1 |
關鍵詞 | 釤-153-EDTMP; 品質管制; 生物體; [fedf]Sm-EDTMP; Freeze dried kit; Biodistribution; |
語文 | 英文(English) |
英文摘要 | An instant kit method was developed for the preparation of �筣m-EDTMP complex proposed to palliate pain resulting from osteoblastic bone cancer. Factors affecting radiochemical purity and stability of the complex as the molar ratio of Sm: EDTMP, pH and incubation period prior to kit preparation were also analyzed by paper and thin layer chromatography. Production of �� Sm using different forms of target material was also investigated. Biodistributions in rats show the �� Sm-EDTMP complex is an excellent bone agent. |
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