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- Coexistent Bullous Pemphigoid and Systemic Lupus Erythematosus: The Diagnostic Dilemma
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題名 | Coexistent Bullous Pemphigoid and Systemic Lupus Erythematosus: The Diagnostic Dilemma=類天疱瘡合併全身性紅斑性狼瘡:診斷上的為難 |
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作者 | 黃靖媛; 陳自強; | 書刊名 | 中華皮膚科醫學雜誌 |
卷期 | 15:2 1997.06[民86.06] |
頁次 | 頁81-86 |
分類號 | 415.761 |
關鍵詞 | 類天疱瘡; 全身性紅斑性狼瘡; Bullous pemphigoid; Bullous systemic lupus erythematosus; Epidermolysis bullosa acquisita; Dermatitis herpetiformis; |
語文 | 英文(English) |
中文摘要 | 一位74歲的家庭主婦罹患水症,臨床及病理表徵為類天泡瘡,後來又產生全身性紅斑性狼瘡,診斷為類天泡瘡乃是根據1MNaCl浸泡正常人的皮膚標本,以患者血清作間接免疫螢光學檢查,呈現高力價(1:320)IgG抗體沈積在表皮側,這個發現,同時可以區分類天泡瘡合併全身性紅斑性狼瘡及其它的表皮下水泡病,包括水泡型全身性紅斑性狼瘡,後天性表皮分解水泡症及泡疹性皮膚炎。 |
英文摘要 | A vesiculobullous eruption with clinical and histological features of bullous pemphigoid (BP) developed in a 74-year-old housewife with later proved systemic lupus erythematosus (SLE). The diagnosis of BP was based on indirect immunofluorescence studies on 1 M NaCl-split normal human skin showing high titer (1:320) IgG deposition along epidermal roof. This finding also discriminates between BP associated with SLE and other subepidermal bullous diseases, including bullous SLE, epidermolysis bullosa acquisita and dermatitis herpetiformis. |
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