頁籤選單縮合
題 名 | 乙型交感神經阻斷劑眼藥對血漿脂蛋白的影響=Studies on the Relationship Between Topical β-Blockers and Serum Lipoprotein |
---|---|
作 者 | 汪正光; 謝瑞玟; | 書刊名 | 中華民國眼科醫學會雜誌 |
卷 期 | 36:2 1997.06[民86.06] |
頁 次 | 頁79-83 |
分類號 | 418.2323 |
關鍵詞 | 乙型交感神經阻斷劑; 眼藥; 血漿脂蛋白; Topical β-blocker; Serum lipoprotein; Intrinsic sympathomimetic activity; ISA; |
語 文 | 中文(Chinese) |
中文摘要 | 治療高血壓的口服乙型交感神經阻斷劑已被證實對血液中的血漿脂蛋白濃度有不 良的影響;而乙型交感神經阻斷劑眼藥又被廣泛地應用在青光眼的治療上,所以我們決定做 此研究來探討乙型交感神經阻斷劑眼藥是否會影響血漿脂蛋白的濃度。 此篇報告共計收集 102 位因眼壓升高而使用乙型交感神經阻斷劑眼藥的患者加以統計分析;分析時將樣本分為 3 組;貝特寧組 (Betoptic, 0.5%,n=32)、美特朗組 (Carteolol, 2%,n=32) 及青眼露組 (Timolol, 0.25%,n=38)。平均追蹤期三組依序為 42.2、40.3 及 42.3 個月,結果顯示乙 型交感神經阻斷劑眼藥並不會造成血液中血漿脂蛋白濃度的升高。故我們相信乙型交感神經 阻斷劑眼藥在有心臟血管相關疾病患者的使用上應是被允許的。 |
英文摘要 | Oral β -blockers taken for the treatment of systemic hypertension had been shown to affect adversely serum lipoprotein levels, so we decided to find the relationship between topical β-blockers and serum lipoprotein in Chinese glaucoma patients. Ninty-six patients with topical β-blocker therapy for raised intraocular pressure were evaluated. They were devided into three groups for data analysis:Betoptic (n=32),Carteolol (n=32), and Timolol (n=38). The average follow-up duration was 41.6 months. In this study , the results showed that there was no significant adverse effect on serum lipoprotein levels in all three groups. We believed that selection of topical β-blockers should not be influnced by lipid changes associated with the oral form of the drug. |
本系統中英文摘要資訊取自各篇刊載內容。