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題 名 | The Effect of Decoction of Artemisia Rheum Gardeniae in a Piglet Model of Hyperbilirubinemia=茵陳蒿湯在小豬高胆紅素血症之療效 |
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作 者 | 郭啟昱; 張博智; 魏正舒; | 書刊名 | 中華民國小兒科醫學會雜誌 |
卷 期 | 37:4 民85.07-08 |
頁 次 | 頁253-256+302 |
分類號 | 414.33 |
關鍵詞 | 高胆紅素血症; 茵陳蒿湯; Hyperbilirubinemia; Decoction of artemisia rheum gardeniae; |
語 文 | 英文(English) |
中文摘要 | 爲了尋找新生兒黃疸的替代性治療法,茵陳蒿湯的療效在動物模式中被測試。15隻4至6天的小豬分成三組(每級5隻):第一組靜脈注射純化的膽紅素(每公觔40毫克)以便模擬新生兒黃疸並且作爲對照組,第二組及第三組分別在打完膽工素之後經胃管喂食(經腸道組)及靜脈注射(非經腸道治療組)茵陳蒿湯;血清中的膽紅素分別在0,0.5,1,2,4及8小時測定。結果顯示這三組在平均年齡及體重均無差異,同時茵陳高湯並不能在8小時之內顯示出療效。本研究顯示茵陳蒿湯治療新生兒黃疸是沒有益處的。 |
英文摘要 | To find an alternative treatment for neonatal hyperbilirubinemia, the effect of a decoction of Artemisia Rheum Gardeniae was tested in an animal model. Fifteen male newborn piglets (four to six days old) were separated into three groups (five piglets/group). The animals of the first group, or Control Group, were intravenously infused with purified bilirubin (40 mg/kg) to simulate neonatal indirect hype rbilirubinemia. The animals of the second and the third groups received the decoction via oral-gastric tube feeding (Enteral Treatment Group) and intravenous injection (Parenteral Treatment Group), respectively, after infusion of bilirubin. Serum bilirubin levels were determined at 0, 0.5, 1, 2, 4 and 8 hours in these groups. The results revealed no significant effect of the decoction on hype rbilirubinemia within eight hours. The implication of this study suggests that a decoction of Artemisia Rheum Gardeniae may be not useful in the treatment of neonatal hyperbilirubinemia. |
本系統中英文摘要資訊取自各篇刊載內容。