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題名 | A Clinical Approach to Gas-Forming Soft Tissue Infections: Report of 14 Cases and Review of the Literature=產氣性軟組織感染的臨床評估 |
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作者 | 楊慶輝; 楊祖光; 翁明章; 彭銘業; | 書刊名 | 醫學研究 |
卷期 | 16:5 1996.03[民85.03] |
頁次 | 頁340-348 |
分類號 | 415.15 |
關鍵詞 | 產氣性軟組織感染; 梭狀芽胞桿菌; 非梭狀芽胞桿菌; 多種微生物的; 黴菌感染; Gas-forming soft tissue infections; Clostridial; Non-clostridial; Polymicrobial; Mycotic infection; |
語文 | 英文(English) |
中文摘要 | 一般而言,在受感染的軟組織內出現氣體代表著組織缺氧,壞死而且癒後不佳。臨床上我們大都認為是厭氧菌-梭狀芽胞桿菌,所引起的感染。然而,事實上目前非梭狀芽胞桿菌引起的產氣性軟組織的感染正持續增加中。這類感染大都為混合性細菌所引起的,包括了需氧性及厭養性的格蘭氏陽性和陰性細菌。此二類在臨床上的表現類似,但是治療的方法及癒後卻大為不同。適時的加以鑑別實有其必要性;而這有賴於臨床表徵的觀察,早期格蘭氏染色的檢查及手術中的發現。而這些正是臨床上用來評估產氣性軟組織感染所賴以最重要的三項原則,也是我們所必需強調的。 |
英文摘要 | Gas-forming soft tissue infection is a grave entity with high mortality rate. Clostridial organisms have been considered as the major causative agents. Recently, non-clostridial infections are, however, more prevalent than clostridial ones previously recognized. Early recognition of the urgently surgical nature of this kind of infections, accompanied with adequate broad-spcetrum antibiotic therapy is the cornerstone of treatment. We reviewed 14 patients proved of severe necrotizing gas-forming soft tissue infections at Tri-Service General Hospital from 1989 to 1994. None of these patients were infected by Clostridial organisms, whereas most of the patients had polymicrobial infections, including Enterococcus, Enterobacter cloacae, S. aureus, Bacteroides fragilis, Pseudomonas aeruginosa and E. coli. Besides, 4 patients had mycotic infections. The overall mortality was 57% (8/14), whereas 2 patients with purely fungal infections had the highest mortality (100%; 2/2). |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。