查詢結果分析
來源資料
相關文獻
- The Different Effect of Salbutamol and Aminophylline on Platelet Activating Factor-Induced Plasma Exudation into Guinea Pig Tracheal Wall and Lumen
- 氣喘症的免疫學觀
- Heliox 在阻塞性肺疾之應用
- PAF拮抗劑
- Platelet Activating Factor Enhances Fertilization Rate with Subzonal Sperm Injection
- Ex Vivo Evidence of Platelet Activating Factor on Ischemic Liver Injury
- 番椒晶素及SNA對人類血小板的抑制作用
- 氣喘症之治療
- 氣喘症
- 鈣離子阻斷劑用於支氣管氣喘症之治療
頁籤選單縮合
題 名 | The Different Effect of Salbutamol and Aminophylline on Platelet Activating Factor-Induced Plasma Exudation into Guinea Pig Tracheal Wall and Lumen=乙二型交感神經性支氣管擴張劑(Salbutamol)和茶鹼類(Aminophylline)對血小板活化因素(Platelet Activating Factor, PAF)誘發之天竺鼠氣管壁及內腔血漿滲出的影響 |
---|---|
作 者 | 劉劍英; 郭漢彬; | 書刊名 | 長庚醫學 |
卷 期 | 19:3 1996.09[民85.09] |
頁 次 | 頁211-216 |
分類號 | 415.4 |
關鍵詞 | 氣喘症; 微細血管滲漏; 血漿液滲出; 血小板活化因子; 抗氣喘症藥物; Asthma; Microvascular leakage; Plasma exudation; Platelet-activating factor; Anti-asthma drugs; |
語 文 | 英文(English) |
中文摘要 | 本實驗檢驗了乙二型交感神經性支氣管擴張劑(Salbutamol),茶鹼類(Aminophylline),和鈣離子阻斷劑(Verapamil)對血小板活化因素(Platelet activating factor, PAF)誘發之天竺鼠氣管壁及其內腔血漿滲出的不同影響。實驗結果發現血小板活化因素會誘發血漿滲出進入氣管壁及其內腔。茶鹼類(Aminophylline)可以清除氣管壁及其內腔因血小板活化因素誘發之血漿滲漏。鈣離子阻斷劑(Verapamil)完全沒有這類作用。乙二型交感神經性支氣管擴張劑(Salbutamol)有意義的減少血小板活化因素誘發血漿滲入氣管壁,而且促進呼吸道內的漿液滲出。本實驗證實了茶鹼類(Aminophylline)會抑制微血管血漿滲出,而乙二型交感神經性支氣管擴張劑(Salbutamol)會促進滲出之血漿通過上皮細胞,減少血漿滲液積留於呼吸道組織內。 |
英文摘要 | We examined the effects of salbutamol, aminophylline and verapamil on plasma exudation into airway wall and lumen in guinea pig trachea isolated in situ. Platelet-activating factor (PAF) (50 ng/kg) induced plasma exudation into both the tissue and lumen. Aminophylline (25 mg/kg) eliminated PAF-induced plasma leakage in the tissue and lumen. Verapamil (500 []g/kg) had neither effect. Salbutamol (160 []g/kg) significantly reduced PAF-induced plasma exudation in the tissue and enhanced plasma recovery in the airway lumen. We conclude that aminophylline inhibited microvascular leakage whereas salbutamol facilitates exudated plasma across epithelium and reduced its accumulation in the tissue. |
本系統中英文摘要資訊取自各篇刊載內容。