頁籤選單縮合
題名 | 假性狂犬病疫苗對肺泡巨噬細胞之影響 |
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作 者 | 陳三多; 王秀如; 劉正義; | 書刊名 | 臺灣畜牧獸醫學會會報 |
卷期 | 61 1993.08[民82.08] |
頁次 | 頁95-104 |
分類號 | 437.243 |
關鍵詞 | 肺泡巨噬細胞; 疫苗; 假性狂犬病; |
語文 | 中文(Chinese) |
中文摘要 | 放線桿菌膜肺炎是本省養豬場很常見的疾病,尤其是常繼發性狂犬病及豬流行性 感冒而使疫情變成非常嚴重,有報告指出,以假性狂犬病疫苗處理豬隻後,再以假性狂犬病 及放線桿菌胸膜肺炎病原攻擊,結果比沒有以假性狂犬病疫苗處理而以假性狂犬病及放線桿 菌胸膜肺炎病原攻擊之情形,其疫情及肺臟病變均較輕,推論可能假性狂犬病疫苗加強了肺 泡巨噬細胞之吞噬能力,而使放線桿菌胸膜肺炎之傷害減輕,故本計劃擬直接觀察肺內巨噬 細胞在經假性狂犬病免疫及未免疫組之不同,本實驗以肺的方法計算肺內巨噬細胞之數目, 結果顯示,豬經假性狂犬病苗免疫後,肺臟內巨噬細胞大量的增加,其增加值甚至達到對照 組之2.14倍,組織切片檢查可見,經假性狂犬病疫苗免疫或未經免疫之豬隻,以放線桿菌攻 擊所產生之肺臟病變,兩組比較,甚為相似,但是,免疫組其肺泡內之巨噬細胞較多,故推 論,豬經假性狂犬病疫苗免疫後較能抵抗放線桿菌傷害,可能是因為免疫後,肺臟內巨噬細 胞大量增加所致。 |
英文摘要 | Actinobacillus pleuropneumonia is an important disease in hog farm, above all, it usually complicated with Pseudorabies infection to cause severe ecnomic loss. A previous study reported that the pigs which were treated with Pseudorabies vaccine, will be more resistant to Actinobacillus pleuropneumonia infection. The possible reason was suggested that the vaccination of Pseudorabies will enhence the phagocytic activity of alveolar macrophages. The aim of this study is to observe the phagocytic activity of alveolar macrophage after Pseudorabies vaccination. The results showed that the number of alveolar macrophages was obviously increased to 2.14 folds than control group after Pseudorabies vaccination. By histopathologic examination, the lesions were similar between Pseudorabies vaccinated and non-vaccinated groups, while they were challenged by Actinobacillus pleuropneumonia. However, the alveolar macrophages were more numerous in vaccinated group than control. Therefore, it was suggested that the vaccinated pigs got more resisitant ability to Actinobacillus pleuropneumonia infection was due to the increase of alveolar macrophages. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。