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題名 | Distribution of Neuropeptide Y Immunoreactivity in the Brain Stem and Spinal Cord of the Rat=神經胜肰Y 在大白鼠腦幹和脊髓的分佈 |
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作者 | 沈清良; | 書刊名 | 師大生物學報 |
卷期 | 23 1988.10[民77.10] |
頁次 | 頁65-84 |
分類號 | 381.48 |
關鍵詞 | 大白鼠; 分佈; 神經胜冴; 脊髓; 腦幹; |
語文 | 英文(English) |
中文摘要 | 本實驗以免疫組織化學法來研究大白鼠腦幹和脊髓內神經胜肽Y的分佈情形。利用NPY抗體之研究發現NPY神經元廣泛的分佈於腦幹中。它的分佈以藍斑核,外綱狀核區和孤獨核為最多。除外三叉神經脊髓徑和枝,脊髓背角等也令許多的NPY神經元。 至於NPY神經纖維亦分佈於腦幹和脊髓的許多區域。其中以孤獨束,三叉神經脊髓徑和核,迷走神經運動核,脊髓背角頂部為最多。本文討論了Catecholamine纖維和NPY纖維分佈上之差異。並略論及NPY神經元之功能。 |
英文摘要 | In order to study the distribution of neuropeptide Y (NPY) like immunoreactivity in the brain stem and spinal cord of the rat, an immunohistochemical localization of this peptide was performed. Using NPY antiserum, it was possible to localize the immunoreactivity neuronal cell bodies located exclusively in the brain stem. This included the locus coeruleus, the region of the lateral reticular nucleus, and the solitary nucleus, which are the areas where most cate-cholaminergic neurons are located. In addition, spinal nucleus and tract of the trigeminal nerve, the midline raphe nuclei and the dorsal horn of the spinal cord also contained NPY neurons. Immunostained fibers were found in several regions in the brain stem and spinal cord. The most densely NPY-like fibers were located in the solitary tract, the spinal nucleus and tract of the trigeminal nerve, the motor nucleus of vagus, and the apex of the dorsal horn of the spinal cord. Some different distribution areas between the catecholaminergic and NPY fibers were discussed. The functions of the NPY neurons were also briefly discussed. |
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