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頁籤選單縮合
題名 | Intrapleural Bleomycin in the Management of Malignant Pleural Effusion=以Bleomycin做肋膜腔內灌注處理惡性肋膜積水 |
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作者 | 許南榮; | 書刊名 | 中華民國外科醫學會雜誌 |
卷期 | 21:3 1988.05[民77.05] |
頁次 | 頁302-308 |
分類號 | 415.43 |
關鍵詞 | Bleomycin; 肋膜腔內灌注; 惡性肋膜積水; |
語文 | 英文(English) |
中文摘要 | 從民國74年1月至75年12月當中,共有21例惡性肋膜積水病人在台中榮總胸腔外科以Bleomycin做肋膜內灌注,我們以30天為評估標準。其中有17個病人在30天內都不再復發呼吸困難,不須再加以任何處理,有效率為80.9%。其中二個病人有發燒高過39℃的現象。使用Bleomycin做肋膜腔內灌注,全身性的副作用少,不會抑制骨髓造血機能,有效率高,對於惡性肋膜積水症狀的解除,是一值得推薦使用的藥物。 |
英文摘要 | Thoracostomy-tube drainage and instillation of bleomycin were utilized in 21 evaluable patients with malignant pleural effusions from January 1985 to December 1986. All the 21 patients were evaluated for response at 30 days. The overall response rate was 80.9%. Toxicities were minimal with fever of more than 39℃ the most common side effect in two patients. Because of its low systemic toxicity, absence of marrow toxicity, and virtual absence of discomfort, bleomycin locally instilled is indicated for use in the management of malignant pleural effusion. |
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