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題名 | Malignant Pleural Effusion as the First Sign of Relapse of Primary Uterine Lymphoma: An Unusual Case Report=以惡性肋膜積水為復發起始表徵之子宮原發性惡性淋巴瘤:一罕見病例報告 |
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作者 | 陳立民; 楊雅堂; 田雨生; 李孝義; | 書刊名 | 中華民國癌症醫學會雜誌 |
卷期 | 16:1 2000.03[民89.03] |
頁次 | 頁5-10 |
分類號 | 417.54 |
關鍵詞 | 惡性肋膜積水; 子宮; 原發性惡性淋巴瘤; Primary uterine lymphoma; Malignant pleural effusion; Chemotherapy; |
語文 | 英文(English) |
中文摘要 | 子宮之原發性惡性淋巴瘤相當罕見,僅佔女性淋巴結外惡性淋巴瘤的 0.6。惡性淋巴瘤患者合併有肋膜積水原本就少,若肋膜積水有惡性淋巴瘤細胞 浸潤,亦即惡性肋膜積水更罕見。本文特別報告一例以惡性肋膜積水為復發起始 表徵之子宮原發性惡性淋巴瘤病例。回顧文獻尚未有此類病例報告。患者為76 歲女性,於診斷子宮原發性惡性淋巴瘤後曾接受6療程之 CHOP(cyclophosphamide,doxo bicin.On Covir與prednisolone]化學治療,並獲完全緩 解。一年後疾病復發且以惡性肋膜積水為復發起始表徵。當再次給予CHOP化學 治療後,依然獲得完全緩解。目前已追蹤1年,患者仍處無病緩解狀態。回顧文 獻並綜合我們對此病例之經驗,子宮之原發性惡性淋巴瘤雖然罕見,但卻是可以 治療的,尤其是給予混合性化學治療。即使疾病復發或擴散,仍舊有效。因此若 能正確的診斷並給予適當的治療,子宮惡性淋巴瘤患者將有很好的預後。 |
英文摘要 | Primary lymphoma of the uterus is extremely rare, accounting for0.6 of extranodal lymphomas of the femates. Pleural effusion (PE) inpatients with lymphoma is relatively rare, malignant PE in patients withlymphoma is even rare. Herein, we report a case of 76-year-old femalewith primary uterine lymphoma. After 6 courses of combination CHOP(cyclophosphamide, doxorubicin, vincristine, and prednisolone)chemotherapy, she got complete remission. However, disease relapse withthe initial presentation of malignant PE was noted one year later. Afteranother 3 courses of CHOP chemotherapy, complete remission wasobtained again. Now the patient is disease free after a I-year follow-up. Toour knowledge, malignant PE as the first sign of relapse for primaryuterine lymphoma has not been reported before. Primary lymphoma ofthe uterus is extremely rare in the English literature, but responded wellto the combination chemotherapy. It still has good response tochemotherapy even in relapsed cases. With our awareness andappropriate treatment patients with uterine lymphoma might have goodprognosis. |
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