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頁籤選單縮合
| 題 名 | Endocrine Function in Children with Intrasellar and Suprasellar Tumors=兒童蝶鞍內及蝶鞍上方腫瘤的內分泌機能 |
|---|---|
| 作 者 | 林美慧; 蔡文友; 陳森輝; | 書刊名 | 中華民國小兒科醫學會雜誌 |
| 卷 期 | 28:4 民76.07-08 |
| 頁 次 | 頁212-218 |
| 分類號 | 417.5933 |
| 關鍵詞 | 兒童; 蝶鞍腫瘤; 內分泌機能; |
| 語 文 | 英文(English) |
| 中文摘要 | 本文收集8例患有蝶鞍內或蝶鞍上方腫瘤的病童,分析手術前或手術後的下視丘一腦垂腺機能,所有於手術前接受下視丘一腦垂腺機能評估的病童,皆至少有一個荷爾蒙分泌異常,其中以生長激素及促性腺激素的異常最常見。手術後則大多數的病童皆有數種荷爾蒙分泌異常。通常手術並不能使原已存在的荷爾蒙異常恢復。我們發現一例患顱咽管瘤的女孩在手衛後第三年出現性早熟現象,這在文獻上並不多見。我們認為患有此類腫瘤的病童於手術前及手術後應接受下視丘一腦垂腺機能的評估,以瞭解其荷爾蒙異常的情況並加以治療。 |
| 英文摘要 | Hypothalamic-pituitary functions in eight children with intrasellar and suprasellar tumors (five craniopharyngioma, one epidermoid cyst, one germinoma, one pituitary adenoma) were studied before and after surgical treatment. Three children who received endocrine function assessment before operation showed at least one hormone deficiency. Growth hormone and gonadotropin secretion were most frequently involved. Multiple hormone deficiencies were present post-operatively in six cases. One girl developed precocious puberty three years after operation, a rare circumstance. Surgical treatment usually did hot reverse preexisting endocrine abnormalities. In one girl, hypothalamic-pituitary dysfunction found one month after operation normalized three years later. This suggests that timing of post-treatment endocrine function assessment is very important. |
本系統中英文摘要資訊取自各篇刊載內容。