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| 題 名 | 護理之家住民困難梭狀桿菌腸道移生與腸道菌叢分析=Clostridioides difficile Gut Colonization and Microbiota Analysis among Residents of Nursing Home |
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| 作 者 | 洪元斌; 蔡進相; 柯文謙; | 書刊名 | 長照感染預防控制雜誌 |
| 卷 期 | 1:1 2022.06[民111.06] |
| 頁 次 | 頁1-8 |
| 分類號 | 419.712 |
| 關鍵詞 | 困難梭狀桿菌; 萬古黴素抗藥性腸球菌; 腸道移生; 護理之家; 長照機構; 擬桿菌科; Clostridioides difficile; Vancomycin-resistant enterococci; Gut colonization; Nursing home; Long-term care facility; Bacteroidaceae; |
| 語 文 | 中文(Chinese) |
| 中文摘要 | 困難梭狀桿菌 (Clostridioides difficile) 是厭氧性革蘭陽性桿菌,體外環境常形成孢子體, 透過醫療照護行為而傳播。困難梭狀桿菌感染相關腹瀉,發生地點多位於醫院、長期照護中 心、或日間照護機構等地方,常被歸屬醫療照護相關疾病。衛福部臺南醫院護理之家一個前瞻 性研究發現,35 位同意加入研究住民,其中 8 位 (22.8%) 發生單獨腸道困難梭狀桿菌移生,其 中一位先後發生困難梭狀桿菌及萬古黴素抗藥性腸球菌移生;8 位後續追蹤,有兩位病患持續 有困難梭狀桿菌移生。另一位只出現萬古黴素抗藥性腸球菌移生。腸道菌叢分析發現擬桿菌科 (Bacteroidaceae) 與困難梭狀桿菌移生有正相關。在長照機構導入宜有效感染管制措施,預防 抗藥性細菌移生或後續感染發生,投予益生菌可能避免困難梭狀桿菌腸道移生。 |
| 英文摘要 | Clostridioides difficile, an anerobic, gram positive bacillus, can form spores in the environment and transmit through healthcare behaviors. C. difficile infections often occurs in the hospitals, long term care facilities, or day-care centers, and thus often are regarded as healthcare-associated infections. In a prospective study in the nursing home of Tainan Hospital, Ministry of Health and Welfare, 35 residents were included, 8 (22.8%) developed C. difficile colonization, and 1 developed consequent colonization of C. difficile and vancomycin-resistant enterococci (VRE). During the follow-up of 8 residents with colonization, 2 had persistent colonization and 1 had VRE colonization. In the microbiota analyses, Bacteroidaceae is positively associated with C. difficile colonization. Therefore, it is important to introduce infection control policies toward to prevent intestinal colonization of antimicrobial-resistant pathogens in long-term care facilities and the use of probiotics, might be beneficial in preventing C. difficile colonization. |
本系統中英文摘要資訊取自各篇刊載內容。