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| 題 名 | 建立以Sysmex XN-10分析健康成人全血球細胞計數及白血球分類的生物參考區間=Establishment Reference Intervals of Hematological Parameters on an Automated Hematology Analyzer Sysmex XN-10 in Healthy Adults |
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| 作 者 | 王一華; 王筱珺; 許呈安; 施佩君; 劉又榕; | 書刊名 | Journal of Biomedical & Laboratory Sciences |
| 卷 期 | 35:1 2023.03[民112.03] |
| 頁 次 | 頁31-38 |
| 分類號 | 415.124 |
| 關鍵詞 | 全血球細胞計數; 白血球分類; 生物參考區間; Complete blood count; Differential count; Reference intervals; |
| 語 文 | 中文(Chinese) |
| 中文摘要 | 全血球細胞計數(complete blood count, CBC)與白血球分類(differential count, D/C)檢驗能幫助臨床診斷或制定治療方向。過去的CBC/DC生物參考區間僅參考儀器原廠建議或文獻來訂定,其範圍不一定完全適用於國人,因此,我們藉由更換機型的時機點,重新建立適合國人的生物參考區間。我們收集2927位健康成人,以Sysmex XN-10分析CBC/DC的數值,利用SPSS軟體進行kolmogorov-smirnov檢定分析並重新制定生物參考區間。本研究結果能提供臨床更準確的診斷依據,也更符合臨床照護之需求,亦可提供國內其他實驗室做為參考的指標。 |
| 英文摘要 | Complete blood count (CBC) test and white blood cell differential count test (D/C) are quite common in regular health checkups. The use of these reference intervals is essential to define disease states and inform treatment decisions. Clinical laboratories commonly base these reference intervals on publications written by experts or information provided by manufacturers. However, differences in population, geography, and laboratory instruments can alter test results. Therefore, it is paramount to make a new set of reference intervals in order to provide the most accurate result for patients. The blood samples were performed by the Sysmex XN-10 automated hematology analyzer (Sysmex Corporation, Kobe, Japan). All CBC and D/C data were retrospectively obtained from health checkups from 2018 to 2019. A total 2927 of healthy individuals (1322 females and 1605 males) were finally used to calculate the new reference intervals by using kolmogorov-smirnov test. The strength of this study is that we establish the reference intervals from Taiwanese population and it is applicable to any laboratory using the Sysmex XN-10 or other instruments with the same method. |
本系統中英文摘要資訊取自各篇刊載內容。