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| 題 名 | Quality of Life in Patients with Nasopharyngeal Cancer after Radiotherapy=鼻咽癌病患放射治療後之生活品質探討 |
|---|---|
| 作 者 | 呂碧鴻; 黃天祥 ; 陳秀蓉; | 書刊名 | 臺灣家庭醫學研究 |
| 卷 期 | 3:2/3 2005.04[民94.04] |
| 頁 次 | 頁88-97 |
| 分類號 | 416.879 |
| 關鍵詞 | 鼻咽癌; 放射治療; 生活品質; Nasopharyngeal cancer; Radiotherapy; Symptoms distress; Quality of life; |
| 語 文 | 英文(English) |
| 中文摘要 | 鼻咽癌(nasopharyngoal cancor, NPC)是台灣常見的癌症,放射療法是它的主要治療策略,但其引發之併發症如口腔炎及後遺症如口乾、甲狀腺功能不足等,對病患身心衝擊甚大。本研究目的在評估放射治療後無復發之鼻咽癌病患之生活品質及其影響因素。43位由耳鼻喉科因疲倦等症狀轉介至內分泌科評估之病患接受歐洲癌症研究與治療組織(The Europoan Organization for Research and Treatment)所發展之生活品質量表:EORTC QLQ-C30 v.3及QLQ H&N35,進行自填式問卷調查。結果顯示:病患平均年齡52.0±8.7歲;17位(39.5%)為男性:接受放射治療後之時間平均為114.4±94.4月。QLQ-C30之生活品質整體評量得分為52.7±24.2。五項功能性量尺中以情緒功能及認知功能(69.0±28.0及70.5±26.2)比較受影響。疲倦、失眠與疼痛是主要的症狀,而NPC特有之症狀中,口乾(72.1±29.9)、唾液黏稠(59.7±36.8)及牙齒問題(48.1±32.8)最為困擾。逐步回歸分析發現QLQ-C30中的角色功能及失眠是主要的預測變項。角色功能可解譯46.2%的變異量,而失眠可解釋12.4%變異量。 總結本研究顯示NPC病患放射治療後具負面情緒、顯著之身體症狀困擾及不佳之生活品質。細心審視QLQ-C30中的顯著症狀都是具有心理意涵在內,所以生理、心理、社會模式之照顧在NPC病患確實是必要的。EORTC QLQ-C30的評量可以協助醫師更加瞭解病患身心狀態提供及時適切的處置,因而能提升照顧品質。 |
| 英文摘要 | Nasopharyngeal cancer (NPC) is prevalent in Taiwan. Radiotherapy is the main treatment modality but its complications and sequelae have great impact on patients. This study assessed their quality of life (QoL) and investigated the influencing factors to their QoL. A total of 43 NPC patients, who were postradiotherapy and recurrence-free, self-assessed their quality of life by the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30 v.3) and the EORTC Head and Neck Cancer Module (EORTC QLQ H&N35). The results showed that the mean age was 52.0±8.7 years, 39.5% was male, the mean duration after radiotherapy was 114.4±94.4 months. The emotional functioning(69.0±28.0) and cognitive functioning (70.5±26.2) were much affected. Fatigue, insomnia and pain were their major concerns. The mean total score of global QoL was 52.7±24.2.The most suffering symptoms specific for NPC were dry month (72.1±29.9), sticky saliva (59.7±36.8) and teeth problem(48.1±32.8). Multiple linear regression analysis revealed that role functioning of QLQC30 (explained 46.2% of variance) and insomnia (explained 12.4% of variance) were the significant predictors of global QoL. In conclusion, our results demonstrate that the NPC patients after radiotherapy had negative emotion, distressful physical symptoms and poorer quality of life. The role functioning and physical distress symptoms played important role in the perception of QoL. Biopsychosocial medical care is essential for improving the QoL. The measurement of EORTC QLQ-C30 could be a useful instrument to early detect patients' physical and psychological concerns. |
本系統中英文摘要資訊取自各篇刊載內容。