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| 題 名 | 以JAK抑制劑Tofacitinib治療新冠病毒疫苗引發全身性禿髮症=Alopecia Universalis Induced by COVID-19 Vaccine Treated with JAK Inhibitor Tofacitinib |
|---|---|
| 作 者 | 林泓科; | 書刊名 | 秀傳醫學雜誌 |
| 卷 期 | 23:2 2024.08[民113.08] |
| 頁 次 | 頁245-249 |
| 分類號 | 415.7752 |
| 關鍵詞 | 新冠病毒; 新冠病毒疫苗; JAK抑制劑; 圓禿; COVID-19 virus; COVID-19 vaccine; JAK inhibitor; Alopecia areata; |
| 語 文 | 中文(Chinese) |
| DOI | 10.30185/SCMJ.202408_23(2).0012 |
| 中文摘要 | 新冠病毒疫苗施打後引發的疫苗注射反應,一般常見如倦怠、頭痛、腹瀉、注射部位紅腫、發燒和肌肉痠痛,本文以個案報告介紹一種少見的副作用alopecia universalis,藉以探討免疫落髮性疾病(alopecia areata, alopecia totalis, alopecia universalis)的病理機轉,其中部份和JAK-STAT pathway相關,後續用JAK抑制劑(tofacitinib,捷抑炎)治療,得到良好的治療成果。 |
| 英文摘要 | Common post-COVID-19 vaccine reactions include general malaise, headache, diarrhea, local injection site reaction, fever, and myalgia. We present a case report about one kind of rare side effect, alopecia universalis, and discuss the pathophysiology of autoimmune alopecia (alopecia areata, alopecia totalis, alopecia universalis). The JAK-STAT pathway plays an important role, and we treated the patient with the JAK inhibitor tofacitinib, and there was a fair treatment response. |
本系統中英文摘要資訊取自各篇刊載內容。