頁籤選單縮合
題 名 | 2017年國內首起腸產毒性大腸桿菌腹瀉群聚事件=First Diarrhea Outbreak of Enterotoxigenic Escherichia coli (ETEC) Infection in Taiwan, 2017 |
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作 者 | 朱建華; 陳婉青; 蘇家彬; 吳芳姿; 魏孝倫; 林宜平; | 書刊名 | 疫情報導 |
卷 期 | 35:9 2019.05.07[民108.05.07] |
頁 次 | 頁114-118 |
分類號 | 412.42 |
關鍵詞 | 腸產毒性大腸桿菌; 腹瀉群聚; 食物中毒; Enterotoxigenic E. coli; Enterotoxigenic Escherichia coli; ETEC; Diarrhea outbreak; Gastro-intestinal symptoms; |
語 文 | 中文(Chinese) |
中文摘要 | 腸產毒性大腸桿菌(Enterotoxigenic E. coli, ETEC),是引起腹瀉疾病的重要致病原,主要發生於旅行者腹瀉或是衛生條件較不佳的國家。疾病管制署於2017年6月14日接獲新北市某高中360名學生,於6月6日至9日參加畢業旅行,返家後陸續有206名學生發生腸胃不適等症狀。採集學生與廚工糞便檢體,其常規腹瀉群聚事件相關病毒及細菌檢驗結果皆為陰性。由於發病者腹瀉症狀個案數遠高於嘔吐症狀,潛伏期中位數為47小時,症狀持續時間中位數為97小時均與ETEC感染極為相似,故進一步檢驗並確定為ETEC感染,為國內首起ETEC腹瀉群聚事件。建議若腹瀉群聚事件常規檢驗項目結果皆為陰性,且臨床症狀、潛伏期與症狀持續期間與ETEC相似時,應將ETEC納入鑑別診斷,以及早診斷病因與評估介入措施。 |
英文摘要 | Enterotoxigenic Escherichia coli (ETEC) is recognized as a leading cause of diarrhea in low-income countries with unsatisfactory sanitary conditions and among travelers to those countries. Taiwan Centers for Disease Control was notified that 206 of 360 students from a senior high school in New Taipei City developed gastro-intestinal symptoms after returning from their graduation excursion during June 6 to June 9, 2017. Stool specimens from ill students and restaurant food handlers were negative for routine enteric pathogens. Because diarrhea was more common than vomiting in this outbreak, the median incubation period was 47 hours, and the median duration of diarrhea was 97 hours, ETEC infection was highly suspected. Specimens were further tested and positive for ETEC, so the first diarrhea outbreak of ETEC infection in Taiwan was confirmed. In order to achieve early treatment and effective prevention, we recommend that ETEC should be considered as the cause of illness when stool cultures are negative for routine enteric pathogens, and the symptoms are similar to ETEC. Additionally, use of PCR techniques along with routine methods to confirm ETEC infection should be considered. |
本系統中英文摘要資訊取自各篇刊載內容。