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頁籤選單縮合
題 名 | 新型口服抗凝血劑在特殊族群之使用=Use of Non-vitamin K Antagonist Oral Anticoagulants in Special Patient Populations with Non-valvular Atrial Fibrillation |
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作 者 | 張雅嵐; 何俊德; 蔡崇弘; 李建瑩; | 書刊名 | 藥學雜誌 |
卷 期 | 35:2=139 2019.06[民108.06] |
頁 次 | 頁71-77 |
分類號 | 418.2321 |
關鍵詞 | 心房顫動; 新型口服抗凝血藥; 慢性腎臟疾病; 老年; Non-vitamin K antagonist oral anticoagulant; |
語 文 | 中文(Chinese) |
中文摘要 | 慢性腎功能不全與老年患者都有較高的栓塞及出血風險,這類族群同時患心 房顫動的比例也較高,2010年新型口服抗凝血藥 (Non-vitamin K Antagonist Oral Anticoagulants, NOACs) 陸續核准後提供了新選擇,雖然相對傳統 Vitamin K antagonists (VKA) 擁有諸多優點,但是臨床上的選擇需考慮:包括年紀、器官功能障礙、用藥 史、交互作用、藥物遵從性等。本文藉由文獻回顧探討慢性腎功能不全與老年族群使 用 NOACs 的有效性與安全性,提供臨床使用參考。 |
英文摘要 | Patients with chronic kidney disease (CKD) and the elderly have an increased risk for bleeding and thromboembolic complications. Among these patients also have a higher prevalence with atrial fibrillation. Non-vitamin K antagonist oral anticoagulants (NOACs), approved by the US Food and Drug Administration (FDA) in 2010 can offer new options for these patients. There are many advantages of NOACs compared with traditional Vitamin K antagonists (VKAs). It is necessary to consider various factors in clinical practice including the following: age, organ dysfunction, medication history, drug interaction, drug compliance, etc. This article is a review literature about the effectiveness and safety of NOACs with patients with CKD and the elderly, and can provide a useful reference in clinical practice. |
本系統中英文摘要資訊取自各篇刊載內容。