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題名 | 帶狀疱疹後神經痛之藥物治療=Pharmacotherapy of Postherpetic Neuralgia |
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作者 | 顏怡婷; 張筱琳; 吳求珍; Yen, Yi-ting; Chang, Hsiao-lin; Wu, Chiu-jen; |
期刊 | 藥學雜誌 |
出版日期 | 20170600 |
卷期 | 33:2=131 2017.06[民106.06] |
頁次 | 頁27-29 |
分類號 | 415.723 |
語文 | chi |
關鍵詞 | 帶狀疱疹後神經痛; Postherpetic neuralgia; |
中文摘要 | 帶狀疱疹為水痘-帶狀病毒感染所引起,約有10-15%的人會演變成帶狀疱疹後神 經痛。疱疹後神經痛發生原因與免疫力及年齡有關,主要發生部位有胸部肋間神經 (T4-T6)、頸神經及三叉神經,多數病人常有痛覺超敏現象。目前臨床上用於治療的 藥物有三環抗憂鬱類藥、抗癲癇藥、鴉片類止痛劑等;另外,可使用外用 lidocaine 及辣椒素。除此之外,抗病毒藥物及帶狀疱疹疫苗可作為預防用藥。 |
英文摘要 | Postherpetic neuralgia (PHN) is a complex neuropathic pain derived from herpes zoster. It estimates to occur in 10-15% of patients. After an initial infection, the varicella-zoster virus moves to dorsal root ganglion, where it remains undetected. The depression of immune system or disease can trigger reactivation of the virus which causes herpes zoster. The thoracic (especially T4 to T6), cervical, and trigeminal nerves are most commonly affected areas. Symptoms may include allodynia. The choices for the medicine in the individuals with PHN are tricyclic antidepressants, anticonvulsants, opioids and external patches. Moreover, antiviral medicines or vaccine can help prevent the occurrence of herpes zoster. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。