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題名 | 益多酚頭等茶的功效性試驗--不易形成體脂肪之動物評估=Efficacy Trials of No.1 EGCG Green Tea |
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作者 | 吳柏龍; 李筱萍; 李志文; 涂茂園; Wu, Po-long; Lee, Hsiao-ping; Li, Chih-wen; Tu, Mao-yuan; |
期刊 | 石油季刊 |
出版日期 | 20161200 |
卷期 | 52:4 2016.12[民105.12] |
頁次 | 頁123-130 |
分類號 | 341.96 |
語文 | chi |
關鍵詞 | 益多酚頭等茶; 不易形成體脂肪; 高熱量飲食; Green tea; Body fat accumulation; High energy diet; |
中文摘要 | 本研究藉由檢測試驗動物體重變化、攝食量、食物利用率、脂肪細胞大小及數目的改變等,了解試驗物質「益多酚頭等茶綠茶」是否具有不易形成體脂肪之功效。試驗動物為 Sprague-Dawley (SD) 大鼠,經高熱量飲食誘導肥胖成功後,進行分組,分別為正常控制組 (ND)、高熱量飲食組(HE)、低劑量組(HE-L,101.3 mL/kg/day,相當於人體 1 倍建議劑量)和高劑量組 (HE-H,506.3 mL/kg/day,相當於 5 倍人體建議劑量),共 4 組。大鼠經連續投予試驗物質 8 週後,將動物犧牲,進行分析。結果顯示高熱量飲食誘導之肥胖大鼠,經連續 8 週投予試驗物質「益多酚頭等茶綠茶」後,不論在 HE-L 組或HE-H 組,均有效降低體重、腹部內脂肪量以及食物利用率等功效 (p<0.05),此外在脂肪細胞大小在 HE-L 組及 HE-H 組相較於 HE 組皆呈現顯著降低(p<0.05)。因此,基於以上的結果,推論本公司生技產品「益多酚頭等茶綠茶」在此試驗模式下,可降低腹部內臟脂肪量及脂肪細胞大小、同時可減輕體重以及降低食物利用率,故具有不易形成體脂肪之功效。 |
英文摘要 | In order to understand whether green tea can prevent body fat accumulation, we monitored body weight change, food consumption and food utilization of animals, as well as size and number changes of fat cells. Obese Sprague-Dawley rats induced by high energy diet were divided into four groups: normal diet group (ND), high energy diet group (HE), low-dose group (HE-L, 101.3 mL / kg / day, equivalent to 1 times of the recommended human dose) and high-dose group (HE-H, 506.3 mL / kg / day, equivalent to 5 times of the recommended human dose). Rats were continuously administered with green tea for 8 weeks, then the animals were sacrificed and analyzed. The results showed both HE-L or HE-H groups had lower body weight, abdominal fat amount and food utilization as compared to HE group. In addition, the sizes of fat cells in HE-L and HE-H groups were significantly smaller than that in HE group. This study reveals CPC's green tea products could prevent body fat accumulation and could improve dyslipidemia induced by high-fat diet, which has the potential to be the anti-obesity functional food. |
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