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題 名 | 益多酚頭等茶的功效性試驗--調節血脂功能之動物評估=Efficacy Trials of No.1 EGCG Green Tea (II) |
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作 者 | 吳柏龍; 李筱萍; 李志文; 涂茂園; | 書刊名 | 石油季刊 |
卷 期 | 53:1 2017.03[民106.03] |
頁 次 | 頁115-125 |
分類號 | 341.96 |
關鍵詞 | 益多酚頭等茶; 總膽固醇; 三酸甘油酯; 低密度脂蛋白膽固醇; Green tea; Cholesterol; Tri-acyl glycerol; Low density cholesterol; |
語 文 | 中文(Chinese) |
中文摘要 | 本試驗主要探討試驗物質「益多酚頭等茶綠茶」之調節血脂功效,將 9週齡之雄性倉鼠分成 4 組,包含正常組 (一般飼料)、負對照組 (高油脂高膽固醇飼料)、試驗物質低劑量組 (120.9 mL/kg) 及高劑量組 (604.3 mL/kg),每組各 6 隻試驗動物。經口投予試驗物質及攝食高油脂高膽固醇之混合飼料 6週後,進行血液之三酸甘油酯 (triglyceride, TG)、總膽固醇 (total cholesterol, TC)及血脂相關指標分析,來探討試驗物質「益多酚頭等茶綠茶」是否初步具有降低血脂功能。試驗結果顯示,餵食試驗物質劑量組於第 3 週開始至第 6 週皆具有降低血液中總膽固醇(TC)、三酸甘油酯(TG)及低密度脂蛋白膽固醇(LDL-C)之功效。低密度脂蛋白膽固醇與高密度脂蛋白膽固醇比 (LDL-C/HDL-C)於第 6 週與負對照組相比各劑量組皆有下降的效果。而高密度脂蛋白膽固醇與總膽固醇比(HDL-C/TC),僅試驗物質高劑量組相較於負對照組於第 6 週有顯著的上升效果。因此,本試驗初步證實試驗物質「益多酚頭等茶綠茶」初步具有調節血脂能力之功效。 |
英文摘要 | The commercial drink product of green tea from Bio-CPC is used to test its ability of reducing cholesterol accumulation in the mouse's blood. The Syrian Hamster mice are divided randomly into 4 groups: normal diet group (ND), high energy diet group (HE), low-dose group (HE-L, 120.9 mL / kg / day, equivalent to 1 times of the recommended human dose) and high-dose group (HE-H, 604.3 mL/kg, equivalent to 5 times of the recommended human dose). Each group has at least 6 mice. After a 6-week treatment, the mouse that administers with green tea shows the reduced concentrations of total cholesterol, tri-acyl glycerol and LDL-C in their blood than the control mouse. The mice on fat diet (HE) are found to have ~3 times more cholesterol and tri-acyl glycerol concentrations than that on normal diet (ND). Moreover, the low density cholesterol (LDL) concentrations of mice, in both HE-L and HE-H groups, are significantly less than the HE group. These results demonstrate that this commercial green tea drink can effectively lower the blood tri-acyl glycerol, cholesterol, and LDL concentrations in Syrian Hamster mice. |
本系統中英文摘要資訊取自各篇刊載內容。