查詢結果分析
來源資料
相關文獻
- 嗜伊紅性與非嗜伊紅性白血球氣喘在致病機轉與治療上的差異
- Airway Hyperreactivity Modulated by Immunotherapy with Denatured Ovalbumin in Ovalbumin-Sensitized Guinea Pigs
- 過敏性氣喘
- 麻杏甘石湯對塵蟍誘發氣喘天竺鼠之影響
- 各年齡層氣喘病人食物過敏率與過敏程度之研究
- The Anti-Inflammatory Effect of a Long-Acting Theophylline (Unidur) in Patients with Bronchial Asthma
- 腎氣丸對塵蟍激發喘天竺鼠呼吸道發炎與免疫之影響
- 如何改善老年人氣喘病的療效
- 小兒氣喘處置之最新發展
- 氣喘的另類治療
頁籤選單縮合
題名 | 嗜伊紅性與非嗜伊紅性白血球氣喘在致病機轉與治療上的差異=Differences in the Pathophysiology and Treatment between Eosinophilic and Non-Eosiophilic Asthma |
---|---|
作者姓名(中文) | 曾敬閔; 蕭光明; 陶啟偉; 彭殿王; | 書刊名 | 內科學誌 |
卷期 | 27:2 2016.04[民105.04] |
頁次 | 頁64-67 |
分類號 | 415.425 |
關鍵詞 | 氣喘; 嗜伊紅性白血球氣喘; 非嗜伊紅性白血球氣喘; 分型; Asthma; Eosinophilic asthma; Non-eosinophilic asthma; Phenotype; |
語文 | 中文(Chinese) |
中文摘要 | 氣喘是一種慢性氣道炎症疾病,通常會有呼吸困難、咳嗽、胸悶及喘鳴聲等表現。近年來經由非侵入性的痰液誘導技術(induced sputum techniques),分析痰液發炎細胞的類型,發現氣喘的炎症反應是一種異質性的變化,臨床上嗜中性球為主的氣喘病人,通常年紀較大,有抽菸病史,過敏成份較低,經常呈現固定性氣道阻塞(fixed airway obstruction);相對的,嗜伊紅性血球為主的氣喘病人,通常年紀較輕,有較嚴重的氣道過度反應(airwayhyperresponsiveness)。另外,難治性氣喘的呼吸道炎症病變,常以非嗜伊紅性白血球(特別是嗜中性白血球)為主。不同的細胞分型,對於類固醇治療的療效,似有不同的影響,因此評估氣喘的異質性對於治療策略的選擇,十分重要。 |
英文摘要 | Asthma is a chronic airway inflammation disease. Patients present variable symptoms such as cough, chest tightness, shortness of breathing or wheezing. In recent studies by induced sputum techniques, we find that the airway inflammation of asthma is heterogeneous. According to different cell types in induced sputum, such as eosinophil or neutrophil prominent, there is different response of inhaled corticosteroid in different phenotype of asthma patients. Furthermore, it seems that older, smoking history, fixed airway obstruction or non-allergic asthma patients have non-eosinophil profile of sputum. On the contrary, allergic asthma patients usually have dominant eosinophil in induced sputum. In conclusion, different phenotypes of asthma should have different choices of treatment. We need to arrange tailored plans for each asthma patient. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。