頁籤選單縮合
題名 | β-丙胺酸增補對氧化壓力影響之探討=The Effect of β-Alanine Supplements on Oxidative Stress |
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作者姓名(中文) | 邱琴瑟; 郭堉圻; | 書刊名 | 運動研究 |
卷期 | 25:1 2016.06[民105.06] |
頁次 | 頁25-33 |
分類號 | 528.9012 |
關鍵詞 | 肌肽; 組胺酸; 自由基; Carnosine; L-histidine; Free radicals; |
語文 | 中文(Chinese) |
中文摘要 | 激烈運動會產生過多的自由基(free radicals),造成氧化傷害,然而人體骨骼肌中富含肌肽(carnosine)(β-alanyl-L-histidine),是由β-丙胺酸(β-alanine)與組胺酸(L-histidine)所組成的一種雙胜肽,其中組胺酸的咪唑環(imidazole ring)含有較佳的抗氧化活性,能夠蜇合金屬銅離子、緩衝pH值等、增加鈣離子釋放,間接的降低自由基產生。研究指出增補β-alanine能夠增加肌肉中的肌肽含量,促進短時間高強度及中長距離的耐力性運動(3~10分鐘)表現,然而也有研究指出,增補肌肽後對於運動後抗氧化只有些微的正向影響。因此,對於肌肽在人體內的抗氧化機轉仍有待釐清的必要性,另建議未來可針對不同性別、年齡及不同運動方式後,所產生的氧化壓力反應去做探討。 |
英文摘要 | While excess free radicals generated in intensive exercise may lead to oxidative damages, L-histidine, one of the building blocks of the abundant carnosine (β-alanyl-L- histidine, a dipeptide formed by β-alanine and L-histidine) in skeletal muscle, contains an imidazole ring which contributes to good antioxidative activity. It is able to form chelates with copper ions, provide buffering capacity, increase the release of calcium ions, and reduce the formation of free radicals in an indirect manner. Studies have shown that β-alanine supplements increase the level of carnosine in muscle, improves performance in temporary high intensity and moderate to long endurance exercise (which lasts for 3 ~ 10 minutes). However, some researches argued that carnosine supplements are associated with a slight increase in antioxidative capacity after exercise. This controversy warrants more effort on the mechanism of antioxidative activity of carnosine, and it is recommended to focus on the oxidative stress associated with different genders, age, and exercise. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。