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題 名 | 化療藥物引起的腎毒性=Chemotherapeutic Agents Associated Renal Toxicities |
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作 者 | 蔡佩芬; 許育瑋; | 書刊名 | 藥學雜誌 |
卷 期 | 31:1=122 2015.03[民104.03] |
頁 次 | 頁65-70 |
分類號 | 418.31 |
關鍵詞 | 化學治療; 化療藥物; 腎毒性; 腎功能; 急性腎損傷; |
語 文 | 中文(Chinese) |
中文摘要 | 隨著化療藥物的發展,癌症患者在存活率上獲得明顯改善,但也因為化療藥物的 廣泛使用,腎毒性發生的機會也隨之增加。當癌症患者發生腎毒性時,通常會使治療 變的棘手與複雜。雖然臨床上已經有許多可以避免腎毒性的方式,化療藥物引起的腎 毒性依然是癌症患者需要特別留意的問題。臨床人員對化療藥物的腎毒性應有一定的 認識,於治療前辨別腎毒性的高風險患者,並於適當時機採取輸液灌注、電解質補 充,以及避免併用其他的腎毒性藥物,密集監測腎功能等措施,以降低腎毒性發生之 機會。 |
英文摘要 | Survival of cancer patients have improved by the development of chemotherapeutic agents; however, treatment with chemotherapeutic agents also increases the likelihood of renal toxicities, which may consequently complicate subsequent care. Although there are many ways to prevent renal toxicities in clinic, renal toxicities induced by chemotherapeutic agents remains an important issue in cancer patients. In addition to understanding characteristics of chemotherapeutic agents, clinicians should identify patients with high risk of renal toxicities, and provide adequate volume infusion, electrolyte repletion, and serial monitoring of renal function to decrease the risk of renal toxicities. |
本系統中英文摘要資訊取自各篇刊載內容。