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頁籤選單縮合
題名 | 重建參數對單光子斷層影像光子計數及影像解析度之影響分析=Analysis of Reconstructed Parameters Effected Image Resolution and Acquired Photon Counts of SPECT |
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作者 | 傅秋華; 陳泰賓; 王祺元; 王寶英; 陸教義; | 書刊名 | 中華放射線技術學雜誌 |
卷期 | 35:3 2011.09[民100.09] |
頁次 | 頁181-186 |
分類號 | 416.14 |
關鍵詞 | 單光子斷層攝影; 衰減校正; 影像解析度; SPECT; Attenuation correction; Image resolution; |
語文 | 中文(Chinese) |
中文摘要 | 單光子斷層攝影已廣泛應用於核子醫學臨床檢診用途。然而發射光子因穿透組織而造成能量衰減、光子與準直儀接觸面產生之康普吞散射、產生可見光後折射等等物理暨硬體效應,以致單光子斷層影像一直存在著解析度不佳的問題。單光子斷層影像同時存在影像中心與周邊位置其光子計數與解析度有所差異的困擾;因此本研究將針對衰減校正、重建方法、及重建參數等因子,對SPECT重建影像之光子計數與影像解析度的影響進行探討。以西門子伽瑪閃爍攝影機進行直線射源假體實驗。同時以不同參數重建單光子斷層攝影原始影像進行分析比較。影像重建分別以濾波反投射法及疊代法執行,並分別對衰減校正執行與否進行分析。疊代式重建法使用不同的重建參數進行研究分析。單光子斷層軸向影像經過衰減校正,中心部分之光子計數可獲得有效改善。改善程度由25.68%上升至78.79% ,有效縮減中心位置與周邊位置之光子計數差距(p-value = 0.00014);但無法使影像解析度獲得改善(p-value = 0.94)。但適當的影像重建方式可以獲得較好的影像解析度。中心位置與周邊影像解析度之相似程度經由疊代與子集數的增加可由33.73%上升至58.18%。由本研究結果可獲知,於旋轉中心之影像解析度,若以較低的疊代與子集數(Iteration < 8 and Subset < 8 或Iteration < 4 and Subsets < 16)之結果尚不及濾波反投影法,光子計數亦然。但對於周邊影像而言,即使是低疊代與子集數的疊代法對解析度及光子計數皆有明顯之改善。因此建議在執行單光子斷層影像重建時,若靶器官位於受檢體深處位置時應以濾波反投射法或適當給予較高疊代與子集數值之疊代法,以獲得較合理之單光子斷層影像。 |
英文摘要 | SPECT is widely applied to diagnose and prognose on clinical nuclear medicine. However, the resolution of SPECT images are poor because the attenuation of gamma ray energy was made by penetrated human tissues, Compton scattering was occurred by interaction between gamma rays and collimator, the reflection of visible lights, and other physical factors. On the other hand, the resolution and photon counts between central and boundary SPECT images are inconsistency. In this work, the main aim is to study the variation of photon counts and resolution of reconstructed image by analyzing correction of attenuation, reconstructed approaches, and parameters of reconstruction. The phantom of line source was scanned by Siemens gamma camera. Meanwhile, the raw SPECT images were analyzed and compared with different reconstructed parameters. The reconstructed images by applying FBP and OSEM were analyzed with and without attenuation correction. The reconstructed images were investigated by using iterative reconstructed method with different parameters. The central photon counts located on axial images of SPECT after attenuation correction were improved from 25.68% to 78.79%. The photon counts located center and boundary were efficiently closed to each other (p=0.00014). However, the resolution of images was failed to improve (p = 0.94). On the contrary, resolution of images could be improvement by using feasible reconstructed method. The similarity of image resolutions located center and boundary was promotion from 33.73% to 58.18% by increasing numbers of iteration and subsets. In these experimental results, the image resolution of central axis by using FBP was better than those by OSEM (iteration <8 and subset <8 or iteration <4 and subset <16). The photon counts were versa. The resolution and photon counts were obviously enhancement by using iterative approach with small numbers of iteration and subset. Therefore, when imaging target located in deep of scanned subject, the reasonable SPECT images should be reconstructed by using OSEM with higher numbers of iteration and subset or FBP. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。