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題名 | 以磁振造影技術分析椎間盤退化與腰椎多裂肌萎縮對下背痛的影響並評估其相關性=Using MRI to Analyze the Influence of Intervertebral Disc Degeneration and Multifidus Muscle Atrophy on Lower Back Pain and their Relationship |
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作者 | 王基誠; 廖阡佑; 黃武達; 陳素秋; 楊斐適; 莊奇容; | 書刊名 | 中華放射線技術學雜誌 |
卷期 | 37:2 2013.06[民102.06] |
頁次 | 頁83-89 |
分類號 | 416.61 |
關鍵詞 | 椎間盤退化; 磁振造影; T2弛豫時間圖像; 腰椎多裂肌; 氫磁振頻譜; Intervertebral disc degeneration; Magnetic resonance imaging; T2 relaxation time calculated map; Multifidus muscles; Proton magnetic resonance spectroscopy; |
語文 | 中文(Chinese) |
中文摘要 | 本研究的主要目的為利用磁振造影技術,分析椎間盤退化與腰椎多裂肌萎縮對下背痛的影響並評估其相關性,以提供醫師作為臨床診斷的依據與選擇治療方式時的參考。本研究使用PHILIP 3.0 T磁振造影(Magnetic Resonance Imaging, MRI)儀進行常規之腰椎攝影,並以非侵入性的T2弛豫時間圖像(T2 relaxation time Map, T2 Map)、T1加權影像及T2加權影像等來量化及分析椎間盤的退化程度,同時使用氫磁振頻譜(proton Magnetic Resonance Spectroscopy, 1H MRS)來分析腰椎多裂肌的變異程度。受試者年齡為20至50歲,分為主訴下背痛之實驗組與無下背痛症狀之控制組各30位。研究結果顯示下背痛受試者之髓核T2值顯著低於健康受試者(80.3 vs. 99.2 ms, p< 0.01),但腰部多裂肌之脂肪含量則無顯著的差異性(18.0% vs. 13.5%, p= 0.085)。疼痛失能指數與髓核T2值呈現顯著負相關,相關係數為-0.426(p< 0.01),而與BMI、年齡及腰椎多裂肌之脂肪含量則呈現顯著正相關,相關係數分別為0.272(p< 0.05)、0.400(p< 0.01)與0.393(p< 0.01)。另外下背痛受試者之各層(L1至S1)椎間盤髓核T2值亦顯著低於健康受試者,顯示下背痛患者之椎間盤髓核水分子含量皆低於健康受試者,且當髓核T2值下降或是腰椎多裂肌的脂肪含量開始增加的同時,因下背痛而對日常生活所產生的影響也將隨之增高。 |
英文摘要 | This study investigates the correlation between disk degeneration and fatty infiltration of the lumbar multifidus muscles. Results will helpfully serve as a reference for clinical physicians during disk degeneration diagnosis and treatment method selection. Philips 3.0T magnetic resonance imaging (MRI) was employed as the measuring equipment. Techniques, including non-invasive T2 relaxation time map (T2 Map), T1W and T2W images, were utilized to quantify and analyze the degeneration level of the intervertebral disks. Additionally, proton magnetic resonance spectroscopy (1H MRS) was performed to analyze variations in the lumbar multifidus muscles. Subjects aged 20 to 50 were divided into two groups, each with 30 participants: an experimental group that expressed complaints regarding lower back pain, and a control group that did not experience lower back pain. The study results showed that individuals with lower back pain had significantly lower T2 (80.3 versus 99.2 ms, p < 0.01) for the nucleus pulposus compared to that of healthy people. However, the fat content of multifidus muscles did not differ significantly between groups (18.0% versus 13.5%, p = 0.085). We found that disability index for lower back pain was negatively and significantly correlated with T2 for the nucleus pulposus, with a correlation coefficient of -0.426 (p < 0.01). Conversely, it was positively and significantly correlated with BMI, age, and the fat content of multifidus muscles, with the correlation coefficients 0.272 (p < 0.05), 0.400 (p < 0.01), and 0.393 (p < 0.01), respectively. Furthermore, the T2 values for the nucleus pulposus of L1 to S1 of the intervertebral disc in people with lower back pain was also significantly lower than that in healthy people, indicating that the water content of the nucleus pulposus for patients with lower back pain was less than that for healthy individuals. When T2 for the nucleus pulposus decreases, or when the fat content of multifidus muscles increases, the influence that lower back pain has on daily life is exacerbated. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。