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題名 | Quality of Life among Pulmonary Tuberculosis Patients under Treatment in Eastern Taiwan=臺灣東部肺結核病患治療期間生活品質的變化 |
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作者 | 鐘威昇; 李其融; 廖翎聿; 楊文達; | 書刊名 | 臺灣公共衛生雜誌 |
卷期 | 33:1 2014.02[民103.02] |
頁次 | 頁23-35 |
分類號 | 415.462 |
關鍵詞 | 生活品質; 肺結核病患; 副作用; Quality of life; TB patients; Adverse reactions; |
語文 | 英文(English) |
中文摘要 | 目標:評估肺結核病患在不同治療時期的生活品質。方法:本研究以台灣東部民眾為基礎的世代研究。採用世界衛生組織健康相關生活品質簡明版問卷,針對台灣東部地區初診斷的肺結核病患進行研究,研究分三階段追蹤研究,第一階段是開始治療時,第二階段是治療二個月治療時,及第三階段是治療六個月時,分別進行面對面問卷調查。結果:本研究經人體試驗委員會通過,並取得病人知情同意後進行。共有140位肺結核病患,男性為多,平均年齡為48±18.9歲。整體生理範疇從第一階段開始治療時至第二階段下降到最低(12.517±2.832分,11.667±3.179分,p<.001),到第三階段治療六個月時才回升(12.691±2.903分)。社會範疇也是從第一階段開始治療時至第二階段下降到最低(13.618±2.685分,12.899±2.953分,p<.05),到第三階段治療六個月時才回升(13.900±2.552分)。當控制可能干擾變項,病患因藥物引起的肝炎比起沒有肝炎者顯著降低生理範疇(β=2.370,p<.001)、心理範疇(β=2.633,p<.001)、社會範疇(β=4.135,p<.001)及環境範疇(β=3.449,p<.001)。病患因藥物引起的視力模糊比起沒有視力模糊者顯著降低生理範疇(β=2.290,p<.001)、心理範疇(β=2.127,p<.001)、社會範疇(β=1.075,p<.05)及環境範疇(β=1.587,p<.01)。生理範疇隨著年齡每增加10歲顯著下降0.39分(β=0.39,p<.01)。有工作的病人比起沒有工作的病人有顯著較高的生理範疇、社會範疇及環境範疇(分別為β=0.959,p<.05,β=0.815,p<.05,β=0.852,p<.05)。每月高收入的病患比起收入低的病患有比較低的心理範疇分數(β=2.029,p<.01)。結論:肺結核病不僅影響個人健康,而且影響生活品質。健康照護者除了關心病患服藥的順從性,更應謹慎注意及處理藥物的副作用。 |
英文摘要 | Objectives: We evaluate the quality of life (QOL) among tuberculosis (TB) patients during different treatment periods. Methods: We conducted a population based cohort study in Eastern Taiwan. The short version of the World Health Organization quality of life (WHOQOL) questionnaire was administered to TB patients under treatment at 3 periods: during an initial treatment period, at a 2-month treatment period, and after a 6-month treatment period. Results: 140 TB patients were interviewed after approval by institutional review boards and interviewee informed consents. The average age of the patients was 48.9 years (SD=18.9 years) and more than half of them were men. Physical domain scores decreased significantly from the initial treatment to the 2-month anti-TB treatment (12.517±2.832, 11.667±3.179, p<.001), and then increased after a 6-month treatment (12.691±2.903). Social domain scores also significantly decreased from the initial treatment to the 2-month anti-TB treatment (13.618±2.685, 12.899±2.953, p<.05), and then increased after 6 months of treatment (13.900±2.552).While controlling probable factors affecting the 4 domain scores related to QOL, drugs related hepatitis reduced physical (β=2.3700, p<.001), psychological (β=2.633, p<.001), social (β=4.135, p<.001), and environmental domain scores (β=3.449, p<.001) and blurred vision significantly reduced physical (β=2.290, p<.001), psychological (β=2.127, p<.001), social (β=1.075, p<.05), and environmental domain scores (β=1.587, p<.01). Physical domain scores significantly decreased as age increased per 10-year (β=0.39, p<.01). The patients employed exhibited significantly higher scores of physical, social, and environmental domains compared than those who were unemployed (β=0.959, p<.05, β=0.815, p<.05, and β=0.852, p<.05 respectively). The patients with a higher income showed fewer scores of psychological domain (β=2.029, p<.01) compared than those who having a lower income. Conclusions: TB affected individual health and QOL, although patients underwent effective treatment. Healthcare workers should be concerned regarding the adverse reactions of anti-TB drugs. |
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