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題名 | Elevated CEA in a Breast Cancer Patient with Overlooked Mixed Medullary-Papillary Thyroid Carcinoma=乳癌病患術後因癌胚抗原升高而診斷出混合性髓質性及乳突狀甲狀腺癌 |
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作者 | 陳威宇; 林靖南; Chen, Wei-yu; Lin, Ching-nan; |
期刊 | 臺灣癌症醫學雜誌 |
出版日期 | 20130600 |
卷期 | 29:2 2013.06[民102.06] |
頁次 | 頁100-104 |
分類號 | 415.138 |
語文 | eng |
關鍵詞 | 乳癌; 癌胚抗原; 混合性髓質性及乳突狀甲狀腺癌; Breast cancer; Carcinoembryonic antigen; Mixed medullary-papillary thyroid carcinoma; |
中文摘要 | 癌胚抗原(Carcinoembryonic antigen,簡稱 CEA)是一常見的胃腸道和乳腺惡性腫瘤 的腫瘤標記。對於有持續性 CEA 升高的患者,醫師通常會進行一系列的檢查,以期找到 臨床表徵並不明顯的潛在性惡性腫瘤。然而,高 CEA 血中濃度也可見於一些良性的狀況。 我們在此報告一個乳癌患者,在接受手術及化療後有持續性的血清 CEA 升高現象。在經 過一系列檢查之後,發現病人有一混合性髓質性及乳突狀甲狀腺癌,並成功進行手術治 療。對於有高血清 CEA 的患者,神經內分泌腫瘤,如甲狀腺髓質癌,應列入鑑別診斷。 FDG-PET 掃描可能是一個檢測隱匿性甲狀腺髓質癌的理想工具。 |
英文摘要 | Carcinoembryonic antigen (CEA) is a tumor marker commonly associated with gastrointestinal and breast malignancy. For patients with persistent elevated CEA, a series of examinations should be performed in order to find a possible underlying occult malignancy that may not be clinically apparent. However, high CEA levels can also be found in benign conditions. We present a patient with persistently elevated CEA after breast cancer surgery and chemotherapy. Following an extensive survey, an overlooked mixed medullary-papillary thyroid carcinoma was identified as the cause of the elevated CEA, which was successfully treated with surgery. For patients with an elevated CEA, a tumor of neuroendocrine origin should be considered, such as medullary thyroid cancer (MTC). In order to facilitate accurate diagnosis, an FDG-PET scan may be an ideal tool to detect occult MTC. |
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