查詢結果分析
來源資料
相關文獻
- Competing Causes of Death in Patients with Oral Cavity Cancer in a Single Cancer Center in Taiwan
- 檳榔的禍患與口腔癌的防治
- 預後營養指數在結腸直腸手術的價值
- An Overview of the Detection and Screening of Oral Cancer and Precancer
- Acquired Immunodeficiency Syndrome and Cytomegalovirus Gastritis in a Patient with Decompensated Liver Cirrhosis and Hepatocellular Carcinoma: Report of a Case
- 口腔黏膜下纖維化之流行病學
- 慢性B型肝炎患者舌下絡脈現代化之研究--並探討合併與未合併肝硬化患者之差異
- 類胡蘿蔔素對檳榔嚼塊萃取物誘發倉鼠口腔癌症之預防效果
- 檳榔嚼食行為與滿州鄉鄉民口腔癌前病變的關係
- 在臺灣控制肝細胞癌及肝硬化盛行有關的研究與措施及其成效
頁籤選單縮合
題 名 | Competing Causes of Death in Patients with Oral Cavity Cancer in a Single Cancer Center in Taiwan=臺灣單一癌症中心口腔癌病人的競爭性死因研究 |
---|---|
作 者 | 張沛泓; 葉光揚; 黃仁聖; 黃彥閔; 張悅詩; 王正旭; | 書刊名 | 臺灣癌症醫學雜誌 |
卷 期 | 29:1 2013.03[民102.03] |
頁 次 | 頁14-21 |
分類號 | 416.89 |
關鍵詞 | 口腔癌; 死亡率; 肝硬化; 合併症; B型肝炎; 檳榔; Oral cavity cancer; Mortality; Liver cirrhosis; Comorbidity; Hepatitis B; Betel quid; |
語 文 | 英文(English) |
中文摘要 | 背景:口腔癌病患的物質濫用情形如吸煙、酗酒和檳榔在台灣是非常普遍存在的問題。 病患本身的疾病對於口腔癌的存活率佔有很重要的因素。這項研究的目的是探討口腔癌 患者的死亡原因,尤其著重在非死於口腔癌的死因。 方法:我們回顧性分析 2007 年至 2009 年的 167 位第 I 期至 IVB 期口腔癌症患者,在本 院接受治癒性的治療,並追蹤到 2011 年 12 月。我們藉由回顧病歷及死亡證明書的方式 來確認這些患者死亡原因的記錄。 結果:在平均追蹤 32.1 個月後,有 51 人死亡;其中 32 例 (62.7%) 是死於口腔癌疾病復 發及進展,其他 19 例 (37.3%) 是死於非癌症相關。在死於非癌症部分,病患死於治療相 關毒性 (7 例) 是最主要的原因,而肝硬化 (4 例) 則是除了治療相關毒性中最常見的死亡 原因。 結論:口腔癌患者在現今跨領域團隊的治療下治癒率是大大的提升,但仍然面臨著除了 疾病本身惡化造成的死亡原因的風險。在治療期間謹慎的照顧病患,以避免治療相關的 毒性導致的死亡是醫療團隊照顧重要的課題。醫師更要有能力評估病患的臨床狀態,以 提供更安全及有效的治療。 |
英文摘要 | Background: Substance abuse such as smoking, excess alcohol consumption and particularly betel quid chewing is popular among patients with oral cavity cancer in Taiwan. Therefore, it is well understood that comorbidities exert a significant impact on survival in oral cavity patients. The purpose of this study was to evaluate the contribution of different causes of death focusing on competing causes (non-cancer) in patients with oral cavity cancer in Taiwan. Methods: We retrospectively analyzed the records of 167 stage I to stage IVB oral cavity cancer patients at our institution who were treated with curative medical management between 2007 and 2009, and followed-up until December 2011. Information derived from case notes and death certificates of these patients were retrospectively analyzed, which provided and described patient illness and cause of death. Results: After a median follow-up period of 32.1 months (range, 2.2 to 55.3 months), a total of 51 deaths occurred; 32 deaths (62.7%) were due to cancer recurrence and progression, while the other 19 (37.3%) patients died of competing causes. Treatment-related toxicity (7 deaths) was the major cause of death other than disease, while liver cirrhosis (4 deaths) was the most common factor contributing to competing mortality other than treatment-related mortality. Conclusions: Patients with oral cavity cancer treated with a multidiscipline combined modality are potentially curable, but face significant risks of mortality from causes other than disease progression. Cautious management of oral cavity cancer patients is required throughout the treatment period to avoid the tragedy of treatment-related mortality. Physicians need to be adept at assessing the physiological and functional capacity of patients with substance abuse and comorbidities, in order to provide safer and more efficacious cancer treatment. |
本系統中英文摘要資訊取自各篇刊載內容。