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題 名 | 血中鈣值濃度與第二型糖尿病男性股骨骨質密度相關性=The Relationship between Serum Calcium Level and Bone Mineral Density of Femur in Type 2 Diabetic Mellitus Male Patients |
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作 者 | 林育玲; 謝惠敏; 劉玉蓮; 賴昱臻; | 書刊名 | 臺灣營養學會雜誌 |
卷 期 | 37:3 2012.09[民101.09] |
頁 次 | 頁93-101 |
分類號 | 415.6681 |
關鍵詞 | 血鈣; 骨質疏鬆症; 第二型糖尿病; Serum calcium; Osteoporosis; Type 2 diabetes mellitus; |
語 文 | 中文(Chinese) |
中文摘要 | 二型糖尿病患是國人常見的慢性病,除了大小血管併發症之外,也有各種骨髓相關併發症,其中最常見的便是骨質疏鬆症。糖尿病治療中很重要的一環是「醫療營養治療」(Medical Nutrition Theray,MNT),但其中主要是針對血糖控制的飲食指引,而對糖尿病患骨質疏鬆症防治的營養建議在過去是較不被重視的。第二型糖尿病其與骨質疏鬆症之間的關聯性相當複雜,且有許多仍未明白了解的地方,而骨質疏鬆症已往被視為「女性」的疾病之錯誤觀念也讓男性骨質疏鬆症被嚴重低估。故本研究目的在探討第二型糖尿病男性患者的骨質密度狀況及其影響因子。本研究為一橫斷性研究,研究對象為40歲以上第二型糖尿病男性患者,收案後安排骨質密度之測定,同時進行體位測量並收取空腹血液樣本進行生化檢查。結果顯示在52位第二型糖尿病男性患者,平均年齡62±8.08歲,糖尿病發病時間10.41±8.72年,糖化血色素平均7.43±0.96%。骨質密度檢查達骨質疏鬆程度的有4位(7.7%),骨量不足的有21位(40.4%),骨質在正常範圍的有27位(51.9%)。腰椎骨質密度分級與各變項間單因子變異數分析-發現腰椎骨質密度與變項皆未有統計顯著差異。股骨骨質密度分級與各變項間單因子變異數分析-發現股骨骨質密度與血中鈣值濃度有統計顯著差異(p < 0.05),又Tukey HSD多重比較顯示骨質密度正常者的血中鈣值濃度最高,骨質疏鬆組與骨量不足組間有統計顯著差異(p < 0.05)。血中鈣值濃度與第二型糖尿病男性股骨骨質密度相關性中顯示骨質密度正常者的血中鈣值濃度最高。增加飲食中鈣質的攝取有助於骨密度的維持與減少骨質疏鬆症的發生。在老年化快速的台灣,第二型糖尿病患者不管女性或男性都應積極防治骨質疏鬆症及相關併發症之產生,在一般的糖尿病的醫療營養治療之外應加強鈣質攝取的衛教以防治骨質疏鬆症之發生。 |
英文摘要 | Type 2 diabetes is a common chronic disease. In addition to vascular complications, there are a variety of bone-related complications such as osteoporosis. Medical nutritional therapy (MNT) mainly focuses on diet guidelines for blood sugar control, but recommendations for preventing osteoporosis are overlooked. Correlations between type 2 diabetes and osteoporosis are quite complex. In the past, osteoporosis was misconceived as a "female" disease, and osteoporosis in men was grossly underestimated. The purpose of this study was to investigate the bone mineral density (BMD) status of male patients with type 2 diabetes and related parameters. This was a cross-sectional study, and subjects were male patients with type 2 diabetes who were older than 40 years old. BMD, anthropometric measurements and fasting blood samples for biochemical tests were collected. Results showed that in 52 type 2 diabetes male patients, the average age was 62 ± 8.08 years, the diabetes duration was 10.41 ± 8.72 years, and the average glycosylated hemoglobin was 7.43 ± 0.96%. Osteoporosis was diagnosed in 4 (7.7%), osteopenia in 21 (40.4%), and a normal BMD in 27 (51.9%). One-way ANOVA analysis of variables of the femur bone density showed a statistically significant difference (p < 0.05) between the femur bone density and serum calcium concentrations. Tukey's honest significant difference multiple comparisons showed that blood calcium concentrations were highest in patients with a normal bone density, and serum calcium concentrations statistically significantly differed (p < 0.05) between patients with a normal bone density and those with osteopenia. Increasing dietary calcium intake can contribute to maintaining the BMD and reducing the occurrence of osteoporosis. Regardless of gender, type 2 diabetes patients should actively prevent and treat osteoporosis. In addition to MNT for diabetes health education, knowledge about adequate calcium intake should also be provided to correct and prevent the development of osteoporosis and its complications. |
本系統中英文摘要資訊取自各篇刊載內容。