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題 名 | Evaluation of Food Safety for Glucosamine HCl and Sulfate in Male Wistar Rats and Investigation of Label and Quality of Commercial Chitinous Products=葡萄糖胺鹽酸鹽和硫酸鹽在雄性大鼠之食用安全評估及市售幾丁質類產品標示和品質調查 |
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作 者 | 黃登福; 鐘秋燕; 洪良邦; | 書刊名 | 臺灣水產學會刊 |
卷 期 | 38:1 2011.03[民100.03] |
頁 次 | 頁55-65 |
分類號 | 346.217 |
關鍵詞 | 幾丁質; 幾丁聚醣; 葡萄糖胺; 食品安全; 重金屬; Chitin; Chitosan; Glucosamine; Food safety; Heavy metal; |
語 文 | 英文(English) |
中文摘要 | 幾丁質類產品已在世界上廣泛被應用於保健食品或食品添加物,為了確保葡萄糖胺之食用安全性,乃以0.25-10%之不同型式葡萄糖胺量餵食雄性大鼠8週,得知即使10%不同型式葡萄糖胺對大鼠的成長、血液特性、肝腎功能指標均無明顯影響。但0.25%以上之不同型式葡萄糖胺對大鼠行動力、血漿葡萄糖和肌酸酐含量、血漿肌酸激酶活性等指標均有下降之作用。對這些指標之作用飼料添加葡萄糖胺硫酸鹽比葡萄糖胺鹽酸鹽者較大。另檢測市售21件幾丁質類產品標市和品質,得知部分幾丁質類產品之鋅、鐵含量較高,產品似有受重金屬汙染之慮。其次,市售幾丁質類產品之去乙醯度介於43-98%,其中一件去乙醯度為<1%,另市售幾丁質類產品中之葡萄糖胺含量介於1-864 mg/g,顯示市售幾丁質類產品之品質標示尚有待改善。 |
英文摘要 | The applications of chitinous products have been developed to use as healthy food or food additive in the world. To certify the edible safety of chitin monomer glucosamine for human, the animal test was then carried out. The male Wistar rats were fed diets with different levels (0.25-10%) of glucosamine for 8 weeks. The results indicated that glucosamine showed no harmful effects on the growth, blood characters, and biological functions of liver and kidney with any level. However, more than 0.25% glucosamine could reduce the behavior activity, the levels of plasma glucose and creatinine, and the activity of plasma creatine kinase in the rats, but increase level of plasma insulin in rats. These indicators are more efficacies when the rats were fed diet with glucosamine sulfate than glucosamine HCl. Furthermore, 21 commercial chitinous samples were examined for heavy metal contents, degree of deacetylation and glucosamine content. It was found that Zn and Fe might contaminate the chitinous samples, ranging <10 ppb-101 ppm and <10 ppb-1,020 ppm, respectively. Except one sample (less than 1%), the degree of deacetylation in the commercial chitinous products ranged 43-98%. The amount of glucosamine ranged from 1 mg/g to 864 mg/g. It means the quality and heavy metal residue need to control for commercial chitinous products. |
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