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題 名 | Molybdate Assisted Ninhydrin Based Sensitive Analytical System for the Estimation of Drugs Containing Amine Group=鉬酸輔助茚三酮為基礎之含胺基藥物分析 |
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作 者 | Nagaraja, Padmarajaiah; Shrestha, Ashwinee Kumar; Shivakumar, Anatharaman; Al-tayar, Naef Ghallab Saeed; | 書刊名 | Journal of Food and Drug Analysis |
卷 期 | 19:1 2011.03[民100.03] |
頁 次 | 頁85-93+105 |
分類號 | 418.4 |
關鍵詞 | 茚三酮; 鉬酸鈉; 藥物分析; 品質管制; 分光光度法; Ninhydrin; Sodium molybdate; Pharmaceutical analysis; Quality control; Spectrophotometry; |
語 文 | 英文(English) |
英文摘要 | ABSTRACT A sensitive spectrophotometric method for the analysis of isoniazid, lisinopril dihydrate, amoxicillin trihydrate, ampicillin trihydrate, glucosamine sulfate, phenylpropanolamine hydrochloride and gabapentin is described. The analysis is based on the reaction of drug molecules with ninhydrin and sodium molybdate mixture to give Ruhemann’s purple product with maximum absorbance (λmax) at 570 nm. The statistical analysis of intra-day and inter-day estimation of drugs as well as comparison with reported methods demonstrated high precision and accuracy of the proposed method. The method was successfully applied to the analysis of pharmaceutical preparations. The procedure was suitable for quality control application. |
本系統中英文摘要資訊取自各篇刊載內容。