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題名 | 利用臺灣蜆(Corbicula fluminea)來監測水中類雌性素物質-雙酚A(bisphenol A)之初步探討=Application of Corbicula fluminea Monitoring Aquatic Xenoestrogen-bisphenol A |
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作者姓名(中文) | 謝宗志; 萬鑫偉; 黃大駿; | 書刊名 | 貝類學報 |
卷期 | 33 2009.12[民98.12] |
頁次 | 頁55-66 |
分類號 | 381.5 |
關鍵詞 | 臺灣蜆; 類雌性素; 雙酚A; 卵黃前質素; Corbicula fluminea; Xenoestrogen; Bisphenol A; Vitellogenin; |
語文 | 中文(Chinese) |
中文摘要 | 臺灣蜆(Corbicla fluminea)是屬於高耐污力、雌雄同體的物種,非常適合作為毒性研究的實驗物種。本研究為了瞭解臺灣蜆是否適合應用監測水中類雌性素(xenestrogen)之指標生物,利用水中常見之類雌性素一雙醃A(bisphenol A, BPA)作為外因性雌性素之試驗用藥,除此之外亦利用17β-estradiol作為比較。實驗中應用不同濃度的BPA曝露臺灣蜆後,於1、3及7天,測定臺灣蜆體內vitellogenin(VTG)濃度來探討BPA對臺灣蜆是否存在類雌性素的功能。試驗同時為了有效探討毒性危害,利用monooxygenase(MO)、glutathione-S-transferase(GST)、aspartate aminotransferase(GOT或AST)及alanine aminotransferase(GPT或ALT)來觀察BPA對臺灣蜆的毒性影響。結果顯示BPA對於臺灣蜆雖有毒性反應,但沒有明顯的毒性危害,同時BPA會誘發臺灣蜆體內VTG生成。實驗初步證實臺灣蜆應可應用於監測水環境中類雌性素物質。 |
英文摘要 | The purpose of this study was to investigate the probably of monitor xenoestrogen in Corbicula fluminea. Individuals of C. fluminea, a common inhabitant of freshwater systems in Taiwan, was exposed to different levels of xenoestrogen-bisphenol A (BPA; 1, 10 and 100 μg L^(-1)) and 100 μg L^(-1) 17β-estradiol, positive control. The detoxication signals which active of monooxygenase (MO) and glutathione-S-transferase (GST), heaptopancreas damage signals which active of aspartate aminotransferase (GOT or AST) and alanine aminotransferase (GPT or ALT), and vitellogenin (VTG), xenoestrogen bioindicator, measured after 1、3 and 7 exposure. According to our findings, induction of a VTG is observed in BPA-treated clam, and not serious detoxication signals and heaptopancreas damage signals in BPA- and 17β-estradiol -treated clam. Our result demonstrated that C. fluminea have high potential for monitoring xenoestrogen especially-bisphenol A. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。