查詢結果分析
相關文獻
- 苗栗縣B群X變異型桿菌性痢疾群突發事件
- 某精神專科醫院 桿菌性痢疾群突發事件調查--外籍看護工之出入境省思
- 2015年臺灣桿菌性痢疾流行病學與抗藥性分析
- Visualization of Chromosome-Sized DNA Molecules by using PFGE for Yeasts Isolated from Infectious Fresh Water Prawn (Macrobrachium rosenbergii de Mann) in Taiwan
- 談桿菌性痢疾之防治經驗
- Investigation of an Outbreak of Pseudomonas Putida Using Antimicrobial Susceptibility Patterns, Pulsed-Field Gel Electrophoresis of Genomic DNA and Restriction Fragment Length Polymorphism of PCR-Amplified rRNA Operons
- 臺灣北部某醫學中心之疥瘡院內群突發
- Kluyvera Cryocrescens院內血流感染群突發之調查
- Characterization of Group D1 Non-typhoid Salmonella Isolates by Serotyping and Pulsed Field Gel Electrophoresis
- 臺灣桃園地區六件宋內志賀菌(Shigella sonnei)群突發之關聯性分析
頁籤選單縮合
題名 | 苗栗縣B群X變異型桿菌性痢疾群突發事件=A Shigellosis Outbreak Caused by S. Flexneri X Variant at a Psychiatric Hospital in Miaoli County |
---|---|
作者 | 廖盈淑; 王佑文; 廖春杏; 許桂貌; 楊文志; 王唯堯; 楊世仰; 邱乾順; Liao, Ying-shu; Wang, You-wun; Liao, Chun-hsing; Shu, Kuei-mao; Yang, Wen-chih; Wang, Wei-yao; Yang, Shih-yan; Chiou, Chien-shun; |
期刊 | 疫情報導 |
出版日期 | 20091100 |
卷期 | 25:11 2009.11[民98.11] |
頁次 | 頁715-725+左773-786 |
分類號 | 415.133 |
語文 | chi、eng |
關鍵詞 | 群突發; 桿菌性痢疾; 脈衝式電泳; DNA指紋圖譜; Outbreak; Shigellosis; Pulsed-field gel electrophoresis; PFGE; DNA fingerprinting; |
中文摘要 | 2008年3月間,苗栗縣某精神專科醫院發生急性腹瀉群突發事件,經實驗室確認為B群痢疾桿菌(Shigella flexneri)所引起之桿菌性痢疾。總計有15名案例,皆為院民,總侵襲率近5%(15/307);其中有症狀者9人(6人檢體陽性),另6名為無症狀感染者(接觸者採檢陽性)。本次疫情實驗室所分析的10株S. flexneri菌株中有1株為2b血清型,9株為X變異型,是台灣境內首次發現由該變異型別引發之群聚感染事件。行政院衛生署疾病管制局(以下簡稱疾管局)針對分離菌株進行藥物敏感性試驗供臨床用藥參考,並利用脈衝式電泳分子分型法分析菌株的DNA指紋圖譜,與疾管局建置之Shigella DNA指紋圖譜資料庫進行比對,確認菌株具有新的DNA指紋圖譜,且2b與X變異型菌株具遺傳上同源關係。為釐清此一新菌型的感染來源,由疾管局第二分局進行相關流行病學調查,惜未能追蹤到最初感染來源,但因菌株為台灣罕見血清型,且菌株圖譜和資料庫之外來2b血清型菌株最為接近,推測菌株可能源於境外。 |
英文摘要 | In March 2008, there was an outbreak of acute diarrhea among patients of a psychiatric hospital located in Miaoli County, Taiwan. The outbreak was caused by Shigella flexneri. A total of 15 cases were identified in the outbreak, all of them were inpatients of the hospital, with an attack rate of approximately 5% (15/307). Among those cases, 9 were symptomatic (6 of the specimens collected were cultured positive) and the other 6 were apparently asymptomatic (contacts tested positive). Of 10 S. flexneri isolates obtained, one was subserotype 2b and 9 were the extremely rare X variant type. This was the first shigellosis outbreak caused by X variant type ever reported in Taiwan. The isolates were subjected to antimicrobial susceptibility testing and pulsed-field gel electrophoresis (PFGE). The isolates were resistant to first-line antimicrobials, including ampicillin, streptomycin, tetracycline, chloramphenicol, and trimethoprim/sulfamethoxazole. DNA fingerprint comparison with those in the Shigella DNA fingerprinting database, established by Taiwan Centers for Disease Control, revealed that the outbreak isolates shared more closely pattern similarity than those in the database and suggested that the isolates of subserotypes 2b and serotype X should be derived from a common recent ancestor. In order to search the infection source, the Second Branch Office of Taiwan CDC carried out an epidemiological investigation. Unfortunately, the investigation failed to identify the source of infection. However, reviewing the fact that the X variant was rare in Taiwan and its DNA fingerprints shares high level of pattern similarity to some imported 2b isolates in the database, inferring that the outbreak strain most likely came from abroad. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。