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題 名 | Surgery of Renal Secondary Hyperparathyroidism=次發性副甲狀腺增生之手術 |
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作 者 | 周逢復; | 書刊名 | 臺灣外科醫學會雜誌 |
卷 期 | 42:4 2009.07-08[民98.07-08] |
頁 次 | 頁205-208 |
分類號 | 415.662 |
關鍵詞 | 副甲狀腺增生; 副甲狀腺機能亢進; Secondary hyperparathyroidism; Mechanism; Total parathyroidectomy plus subcutaneous autotransplantation; |
語 文 | 英文(English) |
中文摘要 | 長期洗腎的病人由於高磷血液,維他命D缺乏及低血鈣而會引發副甲狀腺機能亢進,主要症狀爲皮膚癢、骨痠痛、失眠及全身無力,若次發性副甲狀腺機能合併高副甲狀腺素(>650 pg/m)、高血鈣(>10.1mg/dl),高血磷(>4.6mg/dl)就有手術之適應症,全切除或亞全切除爲有效,符合經濟成本之次發性副甲狀腺機能亢進之手術方法。全切除併皮下自體移植爲簡單可行之手術法,可避免長期服用鈣片及維他命D,若有再發可以簡單發現及移除。 |
英文摘要 | In most patients on long-term dialysis, an increase in secondary hyperparathyroidism (2(superscript nd) HPT) is noted due to hyper-phosphatemia, a deficit of calcitriol synthesis and hypocalcemia. Symptoms of bone pain, skin itching, general weakness and insomnia with high IPTH levels (> 650 pg/ml), hypercalcemia (> 10.1 mg/ml) and hyperphosphatemia (> 4.6 mg/dl) are indications for surgery. Total parathyroidectomy or subtotal parathyridectomy is a cost effective procedure to treat symptomatic 2nd HPT. Total parathryoidectomy plus subcutaneous autotransplantation is an easy method to perform and it can avoid long-life hypoparathyroidism, which total parathyroidectomy without autotransplantaion cannot. It is also easy to find and remove the parathyroid tissue if recurrent hyperparathyroidism at the transplantation site is found. |
本系統中英文摘要資訊取自各篇刊載內容。