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題名 | The Outcome of Stevens-Johnson Syndrome Treated with Corticosteroids: The Experience at Cheng-Hsin General Hospital=以類固醇治療史帝文士強森症候群的成效:以振興醫院之經驗 |
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作者 | 符振中; 楊明松; 周明淵; 李信興; 吳淑靜; 楊茂勳; 熊名琛; | 書刊名 | Medical Journal of South Taiwan |
卷期 | 3:1 2007.06[民96.06] |
頁次 | 頁15-20 |
分類號 | 415.96 |
關鍵詞 | 大水泡; 類固醇; 多行性紅斑; 史帝文士強森症候群; 中毒性表皮壞死鬆懈症; Bullous; Corticosteroids; Erythema multiforme; Stevens-Johnson syndrome; Toxic epidermal necrolysis; |
語文 | 英文(English) |
中文摘要 | 史帝文士強森症候群可能會造成致病性或致死性,一般傳統支持療法有用或不用類固醇。為了證實類固醇治療史帝文士強森症候群有效,我們利用振興醫院21位病例做了此方面的評估,19例是對藥物產生反應;其中影響皮膚面積佔20%至90%,12例有80%的皮膚受到影響,8例有產生水泡病灶的反應,所有21例經類固醇治療後均痊癒,類固醇壓制發炎性反應直到引起反應的藥物被消除;類固醇治療此21位病例不但有療效還可能救命。 |
英文摘要 | The morbidity and mortality of Stevens-Johnson Syndrome (SJS) are considerably high. Traditional management is supportive therapy with, or without corticosterids. To confirm that corticosteroids are beneficial in the treatment of SJS, 21 patients with the syndrome were evaluated. Drug reactions were potential precipitants of SJS in 19 patients. The percent of skin involvement ranged from 20% to 90%, respectively (with 12 having or greater than 80% involvement). Bullous lesions were seen in 8 patients. However, all patients had made completely recovery. Corticosteroids have been found to suppress the inflammatory rejection until the activating agent has been eliminated. Corticosteroid therapy may be lifesaving among these patients. |
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