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題名 | CT Findings of Malignant Gastrointestinal Stromal Tumors with Metastases: An Experience of Cytotoxic Agent and Imatinib Mesylate Treatment=轉移性惡性腸道基質腫瘤電腦斷層的發現:細胞毒性化療劑和Imatinib Mesylate的治療經驗 |
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作者 | 陳志程; 王明宗; 錢尚道; 陳智良; | 書刊名 | 中華放射線醫學雜誌 |
卷期 | 31:3 民95.06 |
頁次 | 頁149-154 |
分類號 | 415.569 |
關鍵詞 | 電腦斷層掃描; 腸道基質腫瘤; Computed tomography; CT; Gastrointestinal stromal tumor; |
語文 | 英文(English) |
中文摘要 | 轉移性腸道基質腫瘤 (GIST) 是腸道最常見的腫瘤,可以發生於腸道各處。我們報告一個78 歲女性患惡性GIST 併腹腔轉移。該病患曾接受兩個階段不同的治療。第一階段使用細胞毒性化療劑;第二階段使用imatinib mesylate (tyrosine 活化激抑制劑)治療。惡性的GIST 有別於其它的腸道間質腫瘤 (mesenchymal tumor) 。它們通常表現為大的,界限清楚的,不均勻的腫塊,且經常轉移至肝臟,網膜和腹膜腔。CT 對GIST 的診斷是很有助益的,Imatinib Mesylate 對於多數轉移性惡性GIST 是有療效的,但對於我們這個病例並無顯著療效。 |
英文摘要 | Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors that can occur throughout the gastrointestinal tract. We reported herein the case of a 78-year-old female patient with malignant GIST (M-GIST) with peri-toneal metastases, treated in two stages: first with cytotoxic agent and second with imatinib mesylate (a tyrosine kinase inhibitor) . M-GISTs are gastroin-testinal tumors that differ from other mesenchymal tumors in the gastrointestinal tract in that they usually present large, well-circumscribed, hetero-geneous masses, and commonly metastasize to liver, omentum, and the peritoneum. CT scan is helpful in the diagnosis of GISTs. Imatinib mesylate treatment for M-GISTs with metastases is beneficial in the majority of cases, while of limited value in our case. |
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