查詢結果分析
相關文獻
- Invasive Fungal Infections in Patients with Acute Leukemia
- Systemic Penicillium Marneffei Infection in a Child with Common Variable Immunodeficiency
- 孤立性蝶竇麴菌症--病例報告
- Intraocular Use of Fluconazole in the Management of Ocular Fungal Infection
- 新製劑的開發--Amphotericin B微脂粒
- 耳朵的黴菌感染與單純疱疹
- 全人工膝關節置換術後之黴菌感染:一例報告
- 鼻顏部接合菌症--病例報告
- Surgical Treatment of Pulmonary Fungal Infection
- 肺麴菌症的支氣管動脈攝影評估及外科治療
頁籤選單縮合
題名 | Invasive Fungal Infections in Patients with Acute Leukemia=急性白血病病患之侵入性黴菌感染 |
---|---|
作者姓名(中文) | 蕭惠樺; 蔡慧珍; 劉益昌; 曾怡婷; 盧柏樑; 楊文棋; 劉大智; 林勝豐; | 書刊名 | The Kaohsiung Journal of Medical Sciences |
卷期 | 22:5 民95.05 |
頁次 | 頁217-222 |
分類號 | 415.635 |
關鍵詞 | 黴菌感染; 急性白血病; 肝脾膿瘍; 麴菌症; Fungal infection; Acute leukemia; Hepatosplenic microabscess; Aspergillus infection; |
語文 | 英文(English) |
中文摘要 | 愈來愈多的侵入性黴菌感染對於癌症病患而言,是一個嚴重的問題。它不僅會引起癌症病患的死亡及損傷,也會影響後續的治療,尤其是急性白血病患更是如此。在此我們報告我們對於急性白血病患合併有侵入性黴菌感染的治療經驗。共有十八位病患於此分析中,其中有十二位是肝脾或腎膿瘍病人,四位鼻竇感染及兩位肺部感染。大部份的病患 (88.9%) 接受含 amphotericin B 在內的治療。其中十三位病患治療後達到完全反應,而於追蹤中均無發現再次黴菌感染,甚至於之後的化學治療中也無發現。在回顧中一共有十一位病患死亡,包括五位病人死於治療黴菌療程中,六位死於後續的白血病復發或頑固型白血病。因此我們認為大部份的病人對侵入性黴菌感染的治療療效不錯且在適當的治療後黴菌感染不會影響後續的化學治療。而病患本身疾病的狀態亦對其預後有相當重要的影響。 |
英文摘要 | Invasive fungal infections, a serious problem among cancer patients, are increasing in incidence, and can cause morbidity and mortality. Such infections may hinder additional treatment, especially for patients with leukemia. We report here our experiences in the management of invasive fungal infection in patients with acute leukemia. A total of 18 patients were enrolled in the study: 12 had microabscesses of the liver and/or spleen and/or kidneys; four had sinonasal infections; and two had pulmonary infections. Most of the patients (88.9%) received amphotericin B during treatment for fungal infection. Thirteen patients achieved complete response without evidence of fungal infection in follow-up. In the study, there were 11 mortalities, including five patients who died during therapy and six who later died as a result of relapse or refractoriness of the leukemia. We suggest that many patients may have a good response to antifungal therapy, and that fungal infection does not have to preclude additional chemotherapy after proper management. The state of the underlying disease has a strong impact on outcome. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。