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題名 | Central Corneal Thickness of Normal-Tension Glaucoma and Non-Glaucoma Populations in Ethnic Chinese=中國人正常眼壓性青光眼病人之中心角膜厚度 |
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作者姓名(中文) | 陳泓橋; 何昭德; 張雪麗; 陳宜信; 吳秀琛; | 書刊名 | 長庚醫學 |
卷期 | 27:1 2004.01[民93.01] |
頁次 | 頁50-55 |
分類號 | 416.748 |
關鍵詞 | 正常眼壓性青光眼; 中心角膜厚度; 近視; 眼壓; Normal-tension glaucoma; Central corneal thickness; Myopia; Intraocular pressure; |
語文 | 英文(English) |
中文摘要 | 背景:角膜厚度之變異會影響眼壓之測量。本研究在比較正常眼壓性青光眼(normal-tension glaucoma)之病人的中心角膜厚度和正常人是否不同。 方法:本研究包括33位正常眼壓性青光眼病人及33為年齡及性別相符的正常人作為對照組。使用超音波角膜厚度俄測量中心角膜厚度。為避免屈光度對眼壓測量之影響,我們將正常眼壓性青光眼病人依屈光度分成兩組,第一組為球面度數介於+2.5至-6.0屈光度;第二組為球面度數大於-6.0屈光度。使用t檢定來比較正常眼壓性青光眼和沒有青光眼的正常人之平均中心角膜厚度。 結果:沒有青光眼的正常人和正常眼壓性青光眼之平均中心角膜厚度(±變異數)分別為554.1(±36.3)及547.2(±31.4)微米,在統計置並沒有差異,p值為.0411。第一組及第二組病人之平均中心角膜厚度分別為545及547.5微米,在統計也沒有差異,p值為0.799。所有正常眼壓性青光眼之病人中,有10位(30%)為高度近視,歸類為第二組,他們的平均年齡為38.5歲,比第一組50歲的人來的低,在統計上有意義,p值為0.0003。 結論:我們景超果顯示,正常眼壓性青光眼之中心角膜厚度和沒有光眼的正常人並沒有不同。 |
英文摘要 | Background: The variations in central corneal thickness can influence intraocular pressure measurement. The aim of our study was to determine whether there is a difference in the central corneal thickness between normal-tension glaucoma (NTG) and non-glaucoma populations. Methods: This prospective study included 33 age- and gender-matched healthy subjects as control subjects. The NTG patients were grouped according to the refractive error into group 1 (spherical equivalent+2.5D~-6.0D) and group 2(spherical equivalent more than -6.0D). Central corneal thickness was measured using a ultrasonic tachymeter. The mean central corneal thickness of the NTG and healthy subjects were compared using the students t-test and Nilcoxon Rank Sum test.. Results: The mean (±SD) central corneal thinness thickness in the healthy subjects and NTG patients was 554.1 (±36.3) and 547.2 (±31.4) microns, respectively. There were no statistical significant differences between these two groups (p=0.411). The median central coneal thickness in the NTG had high myopia (group 2), and their median age was 38.5 years old, which was significantly younger than that of the group 1 patients (50 years old, p=0.0003). Conclusion: This study indicated that there was no significant differences of central corneal thickness between NTG patients and healthy subjects in our clinic. |
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