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題名 | Improved Diagnostic Performance of Thallium-201 Myocardial Perfusion Scintigraphy in Coronary Artery Disease: From Planar to Single Photon Emission Computed Tomography Imaging=改善鉈-201心肌造影在冠心病的診斷--平面到斷層掃描 |
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作者 | 蔡名峰; 高潘福; 曾凱元; Tsai, Ming-fong; Kao, Pan-fu; Tzen, Kai-yuan; |
期刊 | 長庚醫學 |
出版日期 | 20020800 |
卷期 | 25:8 2002.08[民91.08] |
頁次 | 頁522-530 |
分類號 | 414.93、414.93 |
語文 | eng |
關鍵詞 | 冠心病; 單光子電腦斷層掃描; Coronary artery disease; CAD; Single photon emission computed tomography; SPECT; |
中文摘要 | 背景:本研究在於探討鉈-201心肌造影由平面到斷層掃描技術中,對於冠心病的診斷有何改變。 方法:以本院自西元1990年元月至1997年10月間的3262例鉈-201運動心肌造影,回顧240例皆析比較冠狀動脈血管攝影發現。所有240例均於30天內接受冠狀動脈血管攝影與鉈-201運動心肌造影,包括86例單光子電腦斷層掃描和154例平面掃描。 結果:鉈-201運動心肌造影以單光子電腦斷層掃描或平面掃描在診斷個別冠狀動脈(左前下降枝、左迴旋枝、與右冠狀動脈)疾病的敏感度分別為77%/72%、31%/30%、與75%/50%。其診斷單、雙、三條冠狀動脈冠心症的敏感度分別為96%/82%、91%/85%、與96%/90%。 結論:在冠心病診斷罹病冠狀動脈的數目、位置、和範圍上,單光子電腦斷層掃描提供比平面掃描更好的偵測。心臟單光子電腦斷層掃描由於有著較高對比的解析力與更心的分辨重疊心肌能力,使準確判讀鉈-201的非正常分佈得到改善。 |
英文摘要 | Background: This study was performed to compare T1-201 myocardial perfusion single photon emission computed tomography (SPECT) with planar scintigraphy in the diagnosis of coronary artery disease (CAD). Methods: Retrospectively, 240 of 3262 patients, with exercise-redistribution T1-201 myocardial perfusion scintigarphy performed between January 1990 and October 1997, were analyzed to compare T1-201 scintigraphy and coronary arteriography. Within 30 days, all 240 patients underwent both coronary arteriography and exercise-redistribution T1-201 myocardial perfusion scintigraphy with 86 SPECT and 154 planar images acquired. Results: The sensitivities of T1-201 myocardial perfusion scintigaphy in individual coronary arteries including left afterior descending (LAD) artery, left circumflex (LCX) artery, and right coronary artery (RCA), were 77%/72%, 31%/30%, and 77%/50% in the SPECT/planar study groups, respectively. The sensitivities of CAD detection in patients with single-vessel, double-vessel, and triple-vessel disease were 96%/82%, 91%/85%, and 96%/90% in the SPECT/planar study groups, respectively. Conclusion: SPECT images provide greater advantages over planar images for better detection of the number, location, and extent of CAD. Cardiac SPECT does improve the accurate interpretation in abnormal T1-201distributions one to the higher contrast resolution and better separation of overlapping myocardial regions. |
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