查詢結果分析
來源資料
相關文獻
- Needling Revision with Subconjunctival 5-Fluorouracil in Failing Filtering Blebs
- Surgical Outcome of Combined Phacoemulsification and Trabeculectomy
- Effect of Mitomycin C for Combined Trabeculectomy and Phacoemulsification
- Non-Penetrating Trabeculectomy for Open Angle Glaucoma
- Phacotrabeculectomy with Mitomycin C for Cataract and Glaucoma
- 不同形狀之鞏膜瓣其縫線位置對小樑切除術後雷射拆線之影響
- Combined Phacoemulsification with Posterior Chamber Intraocular Lens Implantation and Mitomycin-Augmented Trabeculectomy in Glaucoma Patients
- 原發性隅角開放性青光眼小樑切除術中使用Mitomycin-C與否其成效與合併症的比較
- Mitomycin-C輔助小樑切除術創案經過回憶
- 急性隅角閉鎖性青光眼雷射治療與小樑切除術之比較
頁籤選單縮合
題 名 | Needling Revision with Subconjunctival 5-Fluorouracil in Failing Filtering Blebs=以針頭修整法合併五氟尿嘧啶結膜下注射改善失敗的青光眼小樑切除術 |
---|---|
作 者 | 張雪麗; 侯鈞賀; | 書刊名 | 長庚醫學 |
卷 期 | 25:2 2002.02[民91.02] |
頁 次 | 頁97-103 |
分類號 | 416.748 |
關鍵詞 | 五氟尿嘧啶; 青光眼; 小樑切除術; 針頭修整法; Fluorouracil; Glaucoma; Trabeculectomy; Needling revision; |
語 文 | 英文(English) |
中文摘要 | 背景:五氟尿嘧啶為一抗代謝藥物,能抑制結膜下纖維化,增進小樑切除術之成功率,但於術後早期使用五氟尿嘧啶亦可能使併發症之機會增加。本文研究藥物控制不良之青光眼病患,於小樑切除術後濾過失敗時,施以結膜下注射五氟尿嘧啶合併針頭修整之結果。 方法:我們使用針頭修整法合併五氟尿嘧啶結膜下注射於小樑切除術後水濾過失敗之病患共24人,25隻眼。術前診斷為原發性隅角閉鎖性青光眼4人,原發性隅角開放性青光眼4人,角膜移植術後青光眼8人,外傷性青光眼5人,血管增生性青光眼3人,人工水晶體植入性青光眼1人。結膜下注射五氟尿嘧啶合併針頭修整實施時間,平均為小樑切除術後5.0[]4.0週。 結果:平均追蹤期為8.3[]6.6個月。共接受3.2[]1.2次注射,完全成功有10隻眼睛(佔40%);部分成功的有11隻眼睛(佔44%);所有成功的總和為21隻眼(佔84%)。注射前眼壓為25.98[]8.10毫米汞柱,最後一次回診平均眼壓為15.88[]8.44毫米汞柱。主要併發症為暫時性眼壓過低1人,角膜表皮缺損13人,前房出血3人。 結論:本研究支持五氟尿嘧啶在小樑切除術後作為輔助療法,延後注射的有效性及安全性。 |
英文摘要 | Background: 5-Fluorouracil, an antimetabolic agent, improves the success rate of trabeculectomies by inhibiting subconjunctival fibrosis. However, complications may be associated with early postoperative use. We investigated the outcome of needling revision with delayed subconjunctival 5-fluorouracil in failing filtering blebs after a trabeculectomy in patients with medically poorly controlled glaucoma. Methods: We performed needling revision with subconjunctival 5-fluorouracil injection 5.0[]4.0 weeks after trabeculectomy with failing filtering blebs in 25 eyes of 24 patients. The diagnoses of these patients were primary angle-closure glaucoma (4), primary open-angle glaucoma (4), post-cornea-graft glaucoma (8), traunatic glaucome (5), neovascular gloucoma (3) and pseudophakic glaucoma (1). Results: Total success was achieved in 21 eyes (84%) including complete success in 10 (40%) and qualified success in 11 (44%) after 3.2[]1.2 needling revisions over an average 8.3[]7.0-month follow-up period from the last needling revision. The mean intraocular pressure was 16.0[]8.4 mmHg in the last visit compared with 26.0[]8.1 mmHg before the procedure. Major complications were transient hypotony (1), transient corneal epithelial defect (13) and hyphema (3). Conclusions: This study supports the efficacy and safety of the delayed use of 5-fluorouracil with needling revision for managing failing filtering blebs following a trabeculectomy. |
本系統中英文摘要資訊取自各篇刊載內容。