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- 原發性隅角開放性青光眼小樑切除術中使用Mitomycin-C與否其成效與合併症的比較
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題名 | 原發性隅角開放性青光眼小樑切除術中使用Mitomycin-C與否其成效與合併症的比較 |
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作者姓名(中文) | 黃照文; 謝瑞玟; | 書刊名 | 中華民國眼科醫學會雜誌 |
卷期 | 34:4 1995.12[民84.12] |
頁次 | 頁13-21 |
分類號 | 416.748 |
關鍵詞 | 原發性隅角開放性青光眼; 小樑切除術; Mitomycin-C; Trabeculectomy; Primary open angle glaucoma; Hypotony; |
語文 | 中文(Chinese) |
中文摘要 | 為了抑制青光眼術後增殖組織的形成,Mitomycin-C,一種抗癌藥物已被 施用於小樑切除術中。 本研究收集了56位病人59隻病眼,依術中使用Mitomycin-C與否分為兩個組群 --Standard Group和Mitomycin-C Group。其中Standard Group有30隻眼睛,平均年齡 為24.6±12.4歲;而Mitomycin-C Group有29隻眼睛,平均年齡為26.8±7.9歲。比較兩 組術後的結果,如:成功率,需用藥或再手術的比率,需用藥的種類數,平均眼 壓和視力。結果發現:Mitomycin-C Group有意義地優於Standard Group。但是,術後 的併發症,尤其是低眼壓和低眼壓性黃斑部病變卻是Mitomycin-C Group發生的機 會較高。 |
英文摘要 | To inhibit the ensuing proliferative tissue for-mation after glaucoma surgery, mitomycin-c, ananticancer drug has been applied locally to the ex-posed Tenon capsule and scleral tissues duringtrabeculectomy. We collected 59 eyes of 56 patients who under-went trabeculectomy with or without intraoperativemitomycin-c soaking. Standard group (30 eyes)ranged in age from 14 years to 45 years (mean ageof 24.6 ± 12.4 years) and Mitomycin-C group (29 eyes) from 13 years to 42 years (mean age of 26.8 ±7.9 years). Postoperative outcomes such assuccessful rates (with or without antiglaucoma drugs),percentage of eyes that need medication or additionalsurgery, numbers of medication required, meanintraocular pressure and visual acuity were compared.Mitomycin-C group was significantly better thanStandard group. However, postoperative com-plications of hypotony and hyotonous maculopathywere more frequent in Mitomycin-C group. |
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