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題 名 | 結合相關的臨床實驗於整合分析之模式=A Model Incorporating Related Clinical into a Meta-Analysis |
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作 者 | 許瑞珍; 林春財; 陸海林; | 書刊名 | 嘉南學報 |
卷 期 | 27 2001.11[民90.11] |
頁 次 | 頁113-123 |
分類號 | 412.9 |
關鍵詞 | 整合分析; 經驗貝氏的再抽樣; Meta-analysis; Parametric empirical bayes bootstrap; |
語 文 | 中文(Chinese) |
中文摘要 | 許多整合分析的資料訊息包含超過兩個以上之療法。對於如此資料集傳統的整合 分析僅是估算其中兩個療法之差異性或相對療法。本文中,對於相關的臨床實驗於整合分析 之方法中同時包含三個療法以改進對療法間之差異與異質性之推論。假設不同療法差異比較 有不同的異質性, 我們提供經驗貝氏的再抽樣方法( Parametric empirical Bayes bootstrap ),估算有興趣之相對療效及實驗間的異質性的可信區間做推論的依據。 |
英文摘要 | Many meta-analysis data sets contain the information of more than two treatments. A traditional way is to estimate the difference of two treatments of such data. In this paper, related clinical trials that compare one treatment with other of interest and with the common third treatment are included in the method to improve the inference on both the heterogeneity and treatment difference. The analysis may be carried out by assuming different the difference between treatments heterogenesis for different treatment comparisons. We use parametric empirical Bayesian techniques to construct confidence intervals for the inference on the difference between treatments. |
本系統中英文摘要資訊取自各篇刊載內容。