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來源資料
頁籤選單縮合
題 名 | Bladder-Sphincter Biofeedback as Treatment of Detrusor Instability in Women Who Failed to Respond to Oxybutynin=膀胱與尿道括約肌生理迴饋,用以治療對Oxybutynin無效的不穩定逼尿肌症 |
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作 者 | 王誠; | 書刊名 | 長庚醫學 |
卷 期 | 23:10 2000.10[民89.10] |
頁 次 | 頁590-599 |
分類號 | 416.274 |
關鍵詞 | 膀胱與尿道括約肌生理迴饋; 不穩定逼尿肌症; 骨盆底肌肉訓練; Bladder-sphincter biofeedback; Detrusor instability; Pelvic floor exercise; |
語 文 | 英文(English) |
英文摘要 | Background. This study was designed to determine the efficacy of bladder- sphincter-biofeedback as a secondary treatment for those women with detrusor instability who failed to respond to oxybutynin chloride. Methods. In a prospective non-randomized trial, 31 of 70 women with detrusor instability were assigned to either the study bladder-sphincter-biofeedback training group (n = 16) or to the control pelvic floor exercise group (n = 15) after they had failed to respond to oxybutynin chloride. Results. Thirty (43%) of the 70 women were cured by oxybutynin chloride, and 9 (13%) withdrew due to various side effects. A comparison of cure rates between biofeedback training and pelvic floor exercise groups demonstrated that there were significant differences in objective changes: detrusor pressure (68.75% vs. 0%, p < 0.001), compliance (75.0% vs. 6.67%, p < 0.001), and resting maximal urethral closure pressure (43.75% vs. 6.67%, p < 0.037). Neither the cure rate nor improvement rate of subjective changes (urgency, and frequency and episodes of urge incontinence), significantly differed. Conclusion. Oxybutynin chloride was not well tolerated while bladder-sphincter- biofeedback was well accepted. As a secondary treatment, it appears better than pelvic floor exercise alone and may be the choice of non-surgical treatment in those women who failed to respond to oxybutynin chloride for detrusor instability. |
本系統中英文摘要資訊取自各篇刊載內容。