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頁籤選單縮合
題名 | Molecular Biology of Human Immunodeficiency Virus Type 1=第一型人類免疫不全病毒之分子生物學 |
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作者姓名(中文) | 王維恭; 陳茂源; 莊哲彥; 蔣觀德; 黃立民; | 書刊名 | 微免與感染雜誌 |
卷期 | 33:3 2000.09[民89.09] |
頁次 | 頁131-140 |
分類號 | 414.8 |
關鍵詞 | 第一型人類免疫不全病毒; 分子生物學; Human immunodeficiency virus type 1; HIV-1; Molecular biology; |
語文 | 英文(English) |
英文摘要 | Since the discovery of human immunodeficiency virus (HIV) as the etiologic agent of acquired immune deficiency syndrome (AIDS) more than a decade ago, tremendous progress has been made in various aspects of this virus and its interplay with the host immune system. The advent of potent combination therapy has made it possible to achieve effective and durable control of HIV-1 replication in vivo, yet the persistence of the latent reservoirs pose a new challenge. The recent identifications of several cellular proteins interacting with different viral gene products have not only shed new insights into our understanding of the HIV-1 and the host cell biology, but also provided the bases for developing novel strategies to block HIV-1 replication. It is from this perspective that we review the current understanding of the molecular mechanisms governing the HIV-1 life cycle. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。