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題 名 | Prolonged Neuromuscular Block with Mivacurium in a Patient with Cholinesterase Deficiency=膽素酯酵素不足症病人使用Mivacurium後發生長時間肌無力 |
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作 者 | 黃潔文; 陳捷; 劉雪金; 李育豪; 黃振盛; | 書刊名 | 臺灣醫學會雜誌 |
卷 期 | 99:8 2000.08[民89.08] |
頁 次 | 頁656-658 |
分類號 | 418.21 |
關鍵詞 | 膽素酯酵素不足症; 肌無力; Mivacurium; Cholinesterase deficiency; Prolonged neuromuscular block; |
語 文 | 英文(English) |
英文摘要 | Mivacurium is a short-acting, nondepolarizing neuromuscular blocking agent hydrolyzed by plasma cholinesterase. Because it allows fast recovery, it is a commonly used muscle relaxant for patients undergoing short surgical procedures. We report the case of a 5-year-old boy who underwent outpatient inguinal herniorraphy and developed unexpected prolonged neuromuscular block after the use of mivacurium. He required mechanical ventilation support in the intensive care unit because he could not attain adequate muscle power 1 hour after termination of anesthesia; the muscular paralysis persisted for 5 hours after the bolus dose of 0.3 mg/kg mivacurium. Subsequent investigation revealed an extremely low plasma cholinesterase concentration (115 U/L), and this was later determined to be a congenital condition. This is the first reported case of cholinesterase deficiency diagnosed as a result of general anesthesia in Taiwan. |
本系統中英文摘要資訊取自各篇刊載內容。