查詢結果分析
相關文獻
- Colonoscopic Surveillance in Asymptomatic Persons with Family History of Colorectal Cancer
- 大腸直腸癌篩檢--最新觀念
- Colonoscopic Screening for First Degree Relatives of Patients with Colorectal Cancer
- 大腸直腸癌的篩檢、診斷與追蹤
- 大腸直腸癌之糞便潛血雙重篩檢
- 大腸直腸癌之概況與大腸篩檢之意義
- 大腸直腸癌病患營養篩檢工具之比較
- 您一定要知道的四大癌症篩檢
- 大腸直腸癌篩檢與健康行為相關因素研究--以南部某區域醫院為例
- 大腸直腸癌篩檢:糞便潛血檢查的價值與應用探討
頁籤選單縮合
題 名 | Colonoscopic Surveillance in Asymptomatic Persons with Family History of Colorectal Cancer=以大腸鏡篩檢大腸直腸癌症病患家屬之評估 |
---|---|
作 者 | 葉建裕; 江支銘; 王正儀; | 書刊名 | 中華民國外科醫學會雜誌 |
卷 期 | 32:3 民88.05-06 |
頁 次 | 頁111-115 |
分類號 | 415.138 |
關鍵詞 | 篩檢; 大腸直腸癌; 家族史; Screening; Colorectal cancer; Family history; |
語 文 | 英文(English) |
中文摘要 | 現階段對於無症狀但是有一位一等親家屬罹患大腸直腸癌這樣的族群,並無一定的篩檢計劃。本研究針對這樣的族群做大腸鏡篩檢,並與另一個無家族史,無症狀,僅因陽性潛血反應來求診的族群作比較,發現在409位有家族史的人當中,有41人檢測出有大腸直腸的贅生物(neop1asm),包括3位腺癌,38位為良性腺瘤,其陽性偵測率為10.0%;而129位無家族史的患者中(陽性潛血反應,且平均年齡較大,均可能提高陽性率),有5人檢測出有良性腺瘤,其陽性偵測率為3.9%。有家族史族群明顯高於無家族史者(Odds ratio : 2.76)。在有家族史族群 中,年齡大於40歲者之陽性偵測率14.6%(26/178) 也高於年齡小於40歲者6.5%(15/231)(odds ratio : 2.46)。 由於清除腺瘤可以預防大腸直腸癌,所以雖然僅約10%的病人可以從篩檢中得利,但是其心理解脫的層面卻無法估計。另外43%結腸腫瘤無法由乙狀結腸鏡偵測,69%腫瘤太小(< 5 mm) ,可能在大腸攝影中被忽略,所以大腸鏡仍為篩檢的較佳工具。 |
英文摘要 | The screening policy for first-degree relatives of patients with sporadic colorectal cancer has not been well-defined, especially when those patients are asymptomatic. In order to assess the potential for colonoscopic screening in this high-risk population, 409 asymptomatic person (age range: 18 - 74 years; mean: 39.9 ± 10.1) with only 1 affected first-degree relative received a colonoscopic examination at Chang Gung Memorial Hospital from Nov. 1993 to July 1996. In all, 41 persons, including 3 with adenocarcinoma, 1 with a adenomatous polyposis, 7 multiple adenomas, and 30 single adenomas, were identified. In the same periods, 129 asymptomatic persons (age range: 23 - 81 years; mean: 43.9 ± 11.1 years) who had a positive stool occult blood test and no family history of colorectal cancer received colonoscopic examinations, and 5 patients with 6 adenomas were identified. The positive detection rate in persons with a family histoy (10.0%) is higher than that in persons without a family history (3.9%) (odds ratio=2.76, 95% C.I.=1.07 to 7.15) despite positive stool occult blood and a higher mean age in the latter group, which may have increased risk. Among the individuals with a family history of colorectal cancer, 26 of the 178 older persons (> 40 years old) and 15 of the 231 younger persons (≦40 years old) had colorectal neoplasm. The positive rate in older persons (14.6%) was higher than that in younger persons (6.5%) (odds ratio=2.46, 95% C.I.=1.26 to 4.80). These results confirm the usefulness of family history, with only one member with large bowel neoplasia, in isolating a group at risk for these lesions. This group would most likely benefit from regular cancer and adenomatous polyp screening, particularly when more than 40 years old. |
本系統中英文摘要資訊取自各篇刊載內容。