查詢結果分析
來源資料
頁籤選單縮合
題名 | Wegener氏肉芽腫--三例報告=Wegener's Granulomatosis--Report of Three Cases |
---|---|
作者 | 王凌峰; 戴志峰; 郭文烈; 蔡坤寶; Wang, Ling-feng; Tai, Chih-feng; Kao, Wen-rei; Tsai, Kun-bow; |
期刊 | 中華民國耳鼻喉科醫學雜誌 |
出版日期 | 19990700、19990800 |
卷期 | 34:4 民88.07-08 |
頁次 | 頁357-362 |
分類號 | 416.8 |
語文 | chi |
關鍵詞 | Wegener氏肉芽腫; 壞死性肉芽腫; Wegener's granulomatosis; Necrotizing granuloma; |
中文摘要 | Wegener's氏肉芽腫(Wegener's granulomatosis, WG),是一個以上、下呼吸道的 肉芽腫性發炎,同時可能伴隨著任一器官的血管炎變化來表現的疾病。病程變化很大,可能 是局限型 (limited);也可能是全身型 (generalized),伴有快速展的腎衰謁,或呼吸衰謁 。 且大多數 WG 的病人初期的表現症狀起於頭頸部。 本科在過去 1 年經歷了 3 例 WG,3 例皆為女性,初期的表現以皮膚或肺部的症狀為主,而非平常常見的上呼吸道症狀。由症狀 發生至確定診斷平均為 9 個月。初期的表現從下肢有紫斑、全身無力。 足部有潰瘍須清創 到咳血痰而被懷疑為肺癌等等,臨床表現 3 者之間有相當大的差異,經治療後, 2 例緩解 、1 例死亡。今將其臨床特徵、實險室檢查數據、治療的結果,及目前治療的趨勢一併提出 報告。 |
英文摘要 | Wegener's granulomatosis (WG) is a disease manifested by granulomatous inflammation of the upper and lower respiratory tract, with vasculitis potentially involving any organ ststem. The disease may manifest as a localized process, but it may also be a generalized extensive disease with rapidly progressive renal failure or respiratory insufficiency. Three patients with pathology-proven WG are discussed in this report. The ages of the patients ranged from 20 to 69 years and all were women. The duration from the initial manifestation to diagnosis ranged from 4 to 17 months. lnitial presentations included lower leg purpura, general weakness, foot ulcers which required debriding and suspicion of lung cancer. The clinical courses of the three patients varied greatly. After treatment, two of the patient were in remission and the other patient died of acute renal failure and upper gastrointestinal bleeding. We retrospectively analyzed the records of our three patients for symptons of the disease ad the results of clinical examinations and laboratory test, with special emphasis on the role of head and neck surgeons in diagnosing this disease and the recent advances in managing the disease. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。