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題 名 | Prevention of Hypotension after Spinal Anesthesia for Cesarean Section: Dextran 40 Versus Lactated Ringer's Solution=產婦接受脊髓麻醉導致低血壓之預防:比較Dextran 40與Lactated Ringer's溶液 |
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作 者 | 林朝順; 林子玉; 黃啟祥; 林鈺樺; 林中仁; 詹偉弘; 蔡勝國; | 書刊名 | 麻醉學雜誌 |
卷 期 | 37:2 1999.06[民88.06] |
頁 次 | 頁55-59 |
分類號 | 417.372 |
關鍵詞 | 脊髓麻醉; 低血壓; 剖腹生產; Anesthesia; Spinal; Hypotension; Delivery; Cesarean section; Dextrans; |
語 文 | 英文(English) |
中文摘要 | 背景:此次實驗設計主要在比較術前給予dextran 40與lactated Ringer's solution,對於為剖腹產而接受脊髓麻醉之病人,麻醉後發生低血壓之機率。 方法:六十位美國麻醉醫學會體位評等第一級預備剖腹生產的病人,以隨機的方式分成兩組, 一組於脊髓麻醉前給予500毫升dextran 40,另一組給給予1,000毫升lactated Ringer's solution。以雙盲的方式進行研究。 結果:脊髓麻醉後,病人發生低血壓之機率,於lactated Ringer's solution組為53.3%,於 dextran組為26.7%,P<0.05。治療低血壓所使用ephedrine之平均劑量分別為3.2毫克與15.5 毫克,P<0.05。兩組新生兒以Apgar評分皆為良好而無差異。 結論:對於剖腹產的病人,於脊髓麻醉前使用500毫升dextran 40比起1,000毫升lactated Ringer's solution,更能夠有效降低低血壓發生的機率。 |
英文摘要 | Background: This study was designed to compare the efficacy of 10% dextran 40 with lactated Ringer's (LR) solution in reducing the incidence and severity of hypotension after spinal anesthesia for Cesarean section. Methods: Sixty ASA grade I patients scheduled for Cesarean section were randomized into two groups in a double-blind fashion to receive either 500 ml of dextran 40 or 1000 ml of LR solution prior to induction of spinal anesthesia. Results: The incidence of hypotension was 16 in 30 (53.3%) in the LR solution group and 8 in 30 (26.7%) in the dextran group (P<0.05). The required dose of ephedrine for treatment of hypotension was significantly greater in the LR solution group than in the dextran group (15.5 mg versus 3.2 mg, P<0.05). Neonatal outcome, as determined by Apgar score, was good and similar in both groups. Conclusions: We concluded that 500 ml of dextran 40 is more effective than 1000 ml of lactated Ringer's solution in reducing the incidence of hypotension induced by spinal anesthesia. |
本系統中英文摘要資訊取自各篇刊載內容。