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| 題 名 | Chronic Hepatitis B Exacerbated by Guillain-Barre Syndrome: A Report of Two Cases=慢性B型肝炎急性發作引發Guillain-Barre症候群:2病例報告 |
|---|---|
| 作 者 | 罕華發; 吳肇卿; 霍德義; 高克培; 黃怡翔; 張扶陽; 李壽東; | 書刊名 | 中華醫學雜誌 |
| 卷 期 | 62:9 1999.09[民88.09] |
| 頁 次 | 頁652-656 |
| 分類號 | 415.533 |
| 關鍵詞 | 急性發作; 慢性B型肝炎; 併發症; G-B症候群; Acute exacerbation; Chronic hepatitis B virus; Complication; Guillain-barre syndrome; |
| 語 文 | 英文(English) |
| 英文摘要 | Several neurologic complications involving both the central and peripheral nervous systems due to acute viral hepatitis have been described, but Guillain-Barre (G-B) syndrome occurring as a complication of chronic viral hepatitis is extremely rare. Although it is generally agreed that G-B syndrome develops as an immune- mediated reaction, its exact pathogenesis remains obscure. We report the cases of two patients with chronic hepatitis B virus (HBV) infection acutely exacerbated by the development of G-B syndrome. G-B syndrome was diagnosed by nerve conduction velocity studies, electromyographic studies and a rise in acellular total protein in the cerebrospinal fluid (albumino-cytologic dissociation). In these two patients, we were able to accurately define the relationship between the onset of acute exacerbation of chronic HBV infection and G-B syndrome. The neurologic symptoms of G-B syndrome resolved with the return of liver enzymes to normal. Interferon therapy may be beneficial in relieving neurologic symptoms in patients with HB infection-related G-B syndrome. |
本系統中英文摘要資訊取自各篇刊載內容。