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- Treatment of Pulmonary Atresia with Intact Ventricular Septum in Early Infancy
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- 新生兒病危型--先天性心臟病之介入治療
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題名 | Treatment of Pulmonary Atresia with Intact Ventricular Septum in Early Infancy=嬰兒期治療肺動脈閉鎖合併完整性心室中膈 |
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作者姓名(中文) | 謝王虎; 黃碧桃; 陸振翮; 李必昌; 傅雲慶; 邢學平; 孟春昌; | 書刊名 | 中華醫學雜誌 |
卷期 | 62:9 1999.09[民88.09] |
頁次 | 頁626-632 |
分類號 | 417.5261 |
關鍵詞 | 右心室發育低下; 前列腺素戊壹; 肺動脈閉鎖; Hypoplastic right ventricle; Prostaglandin E[feb5]; Pulmonary atresia; |
語文 | 英文(English) |
英文摘要 | BACKGROUND: Early treatment for the neonate with pulmonary atresia and intact ventricular septum (PA-IVS) is important if a high mortality rate is to be avoided. The treatment includes prostaglandin administration, balloon atrial septostomy, pulmonary valvotomy, a shunting procedure and patch repair for the right ventricular outflow tract (RVOT). This study discusses the early treatment and risk factors of this disease that are essential for assessing the risk of surgery and predicting outcome. METHODS: The medical records, echocardiograms, catheterization data and cineangiograms of 29 patients with PA-IVS diagnosed at our institution from 1987 to 1997 were reviewed retrospectively. Clinical manifestations including age, body weight, sex ratio, type of surgery and outcome were analyzed. RESULTS: Three of four patients with a right ventricular volume of less than 1 ml died, and all patients with a right ventricular volume of greater than 2 ml survived. Four of six patients with a tricuspid valvular area of between 0.25 and 0.5 cm2 died, but patients with an area of greater than 0.5 cm2 survived. One case with a monopartite right ventricle died. Patients with a bipartite or tripartite right ventricle had higher survival rates than those with a monopartite right ventricle. Patients with a the right ventricle dependent coronary sinusoid had a higher risk for mortality, even after surgery, than those with normal coronary circulation. CONCLUSIONS: A small right ventricular volume, the presence of a coronary sinusoid involving the right ventricle, a short linear length of the tricuspid valve and a small area of the tricuspid valve were the risk factors associated with a negative outcome in neonates with PA-IVS. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。